Results 51 to 60 of about 1,076 (281)

Short-term soil amendment by sewage sludge anaerobic digestate in a tomato monoculture suppresses Fusarium vascular wilt disease by changing the taxonomic characteristics of soil microbiota [PDF]

, 2023
Digestate incorporation into topsoil determines soil fertility improvement by changing composition and structure of soil microbiota. However, how microbiota responds to short-term soil amendment by sewage sludge anaerobic digestate (SSD) for suppressing ...
Cancellara F. A., Caranfa D., Cucci G., De Corato U., Lacolla G.   +4 more
core   +1 more source

Germline TP53 Mutations Causing Diamond–Blackfan Anemia: A French Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Diamond–Blackfan anemia is a rare congenital erythroblastopenia typically caused by mutations in ribosomal protein genes. Recently, gain‐of‐function mutations in TP53 have been identified as a novel cause of Diamond–Blackfan anemia. We report two French patients who both harbored a heterozygous TP53 deletion (NM_000546.5: c.1077delA; p ...
Rafael Moisan, Lydie Da Costa, Ludivine David Nguyen, Heloise Chosseler, Audrey Riquet, Benedicte Bruno, Melissa Barbati   +6 more
wiley   +1 more source

Peripheral B Cell Deficiency and Predisposition to Viral Infections: The Paradigm of Immune Deficiencies

Frontiers in Immunology, 2021
In the era of COVID-19, understanding how our immune system responds to viral infections is more pertinent than ever. Immunodeficiencies with very low or absent B cells offer a valuable model to study the role of humoral immunity against these types of ...
Alexandros Grammatikos, Matthew Donati, Sarah L. Johnston, Mark M. Gompels   +3 more
doaj   +1 more source

The Role of Invasive Procedures in the Treatment of Complicated Gastrointestinal Graft‐Versus‐Host Disease in Pediatric Patients

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Gastrointestinal graft‐versus‐host disease (GI GVHD) following hematopoietic stem cell transplant is typically managed with medical therapy, but surgery and angioembolization may be warranted in selected cases with life‐threatening complications.
Gaia Brunetti, Giorgio Persano, Chiara Grimaldi, Pier Luigi Di Paolo, Carmen Malaspina, Francesco Quagliarella, Valerio Balassone, Anna Chiara Iolanda Contini, Gian Luigi Natali, Rita Alaggio, Ivan Pietro Aloi, Tamara Caldaro, Alessandro Crocoli   +12 more
wiley   +1 more source

The Good Soldier švejk Syndrome [PDF]

Journal of the Royal Society of Medicine, 2001
We thank your correspondents for putting flesh on the skeleton we presented in our paper (January 2001, JRSM, pp. 22-25), and for illustrating the extensive knowledge of the Good Soldier Svejk (and Czech culture) among JRSM readers. We are taken to task for regarding Svejk as someone who had at least a forme fruste of psychosis as well as periods of ...
Peter Tyrer, Jo Emmanuel, Nicholas Babidge, Nishi Yarger, Maya Ranger, Jaroslav Blahošr   +5 more
openaire   +1 more source

Thymic Epithelial Tumors: Model of rare tumors for the identification of new biomarkers and novel therapeutic opportunities [PDF]

, 2021
In this thesis, I discuss the identification of new insights and the evaluation of novel treatment opportunities in thymic epithelial tumors, which are widely recognized as rare cancers.
Ottaviano, Margaret
core  

Gut-Thyroid axis: How gut microbial dysbiosis associated with euthyroid thyroid cancer [PDF]

, 2022
Thyroid cancer in humans has a fast-growing prevalence, with the most common lethal endocrine malignancy for unknown reasons. The current study was aimed to perform qualitative and quantitative investigation and characterization of the gut bacterial ...
Fan, Yang, Hayat, Khezar, Hussain, Riaz, Ihsan, Ayesha, Ishaq, Hafiz Muhammad, Li, Huan, Mohammad, Imran Shair, Muhammad, Kiran Sher, Parveen, Rashida, Santos, Ana Cláudia Paiva, Shahzad, Muhammad, Shirazi, Jafir Hussain, Ullah, Shakir, Usman, Muhammad, Xu, Jiru, Yuan, Lu, Zhang, Siruo   +16 more
core   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Lessons Learned From a Delayed‐Start Trial of Modafinil for Freezing of Gait in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Freezing of gait (FOG) in people with Parkinson's disease (PwPD) is debilitating and has limited treatments. Modafinil modulates beta/gamma band activity in the pedunculopontine nucleus (PPN), like PPN deep brain stimulation. We therefore tested the hypothesis that Modafinil would improve FOG in PwPD.
Tuhin Virmani, Lakshmi Pillai, Reid D. Landes, Aliyah Glover, Shannon Doerhoff, Jennifer Kleiner, Mitesh Lotia, Rohit Dhall, Edgar Garcia‐Rill   +8 more
wiley   +1 more source

A brief period of sleep deprivation leads to subtle changes in mouse gut microbiota [PDF]

, 2020
Not getting enough sleep is a common problem in our society and contributes to numerous health problems, including high blood pressure, diabetes and obesity.
Bolsius, Youri G., El Aidy, Sahar, Havekes, Robbert, Raven, Frank   +3 more
core   +1 more source