A Case of Severe COVID-19 in a Patient with Good's Syndrome [PDF]
European Journal of Case Reports in Internal Medicine, 2021 Good’s syndrome is a rare adult-onset combined immunodeficiency. The association of hypogammaglobulinaemia with a history of recurrent infectious or autoimmune manifestations in a middle-aged patient with evidence of a mediastinal mass should lead to the
Maria Duarte +4 more
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Insights from a Case of Good’s Syndrome (Immunodeficiency with Thymoma) [PDF]
Biomedicines, 2023 Immunodeficiency with thymoma was described by R.A. Good in 1954 and is also named after him. The syndrome is characterized by hypogammaglobulinemia associated with thymoma and recurrent infections, bacterial but also viral, fungal and parasitic ...
Roberto Paganelli +6 more
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Clinicopathologic features of Good’s syndrome: Two cases and literature review [PDF]
Open Medicine, 2021 Good’s syndrome (GS) is an immunodeficiency disease, causing thymoma, low or absent B-cells, hypogammaglobulinemia, and defects in cell-mediated immunity.
Chen Yi-Dan +4 more
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Good’s Syndrome: Time to Move on From Reviewing the Past [PDF]
Frontiers in Immunology, 2022 For seven decades, the pathophysiology of Good’s syndrome (GS) has remained a mystery, with few attempts to solve it. Initially described as an association between hypogammaglobulinemia and thymoma, controversy exists whether this is a unique disease, or
Aunonna Kabir +4 more
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Good’s syndrome revealed by recurrent sigmoid diverticulitis [PDF]
European Journal of Case Reports in Internal MedicineThymus is a primary lymphoid organ whose main function is the education of the T lymphocytes. Thymoma is uncommon neoplasia derived from epithelial cells of the thymus. Patients with thymoma frequently present with autoimmune disorders, mostly myasthenia
Hassene Attout +4 more
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Good’s syndrome and infections in a large retrospective cohort of thymoma [PDF]
Frontiers in ImmunologyIntroductionGood’s syndrome (GS) is an immunodeficiency associated with thymoma characterized by hypogammaglobulinemia. The co-existence of recurrent infections may be associated with quality of life and overall survival.
Wenji Jia +9 more
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B cell deficiency in thymoma tissues of Good’s syndrome patients [PDF]
Discover OncologyObjectives Good’s syndrome (GS) is a rare secondary immunodeficiency which is characterized by hypogammaglobulinemia and thymoma. This study aims to investigate the expression and distribution of B cells in thymoma tissue, given that B cells had been ...
Junwu Zhang +4 more
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Significant decreased CXCR3+ phenotype Tfh1 cells in three Good’s syndrome patients [PDF]
Frontiers in ImmunologyBackgroundGood’s syndrome (GS) is a rare acquired immunodeficiency defined by the co-occurrence of thymoma and hypogammaglobulinemia. Follicular helper T (Tfh) cells, a specialized CD4+ T cell subset, play a critical role in supporting B-cell antibody ...
Yanxia Chen +5 more
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Good’s syndrome, a rare form of acquired immunodeficiency associated with thymomas [PDF]
Clinics and Practice, 2019 Good’s syndrome (GS) or thymomaassociated immunodeficiency is a rare clinical entity that should be ruled out in patients with thymoma who develop severe, recurrent bacterial infections and opportunistic viral and fungal infections.
Antonio Tamburello +8 more
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Relapsing cellulitis associated with Campylobacter coli bacteremia in a Good’s syndrome patient: a case report [PDF]
BMC Infectious Diseases, 2022 Background Good’s syndrome (GS) is characterized by immunodeficiency, and patients diagnosed with GS are susceptible to infection or even bacteremia, which is the most evident complication. Campylobacter coli (C.
Lei Jiang, Jia Gao, Pu Wang, Yuliang Liu
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