Results 41 to 50 of about 2,120 (245)

Lactobacillus rhamnosus lowers zebrafish lipid content by changing gut microbiota and host transcription of genes involved in lipid metabolism. [PDF]

, 2015
The microbiome plays an important role in lipid metabolism but how the introduction of probiotic communities affects host lipid metabolism is poorly understood.
Carnevali, O, Cossignani, L, Falcinelli, S, Gioacchini, G, Maradonna, F, Merrifield, DL, Olivotto, I, Picchietti, S, Rodiles, A, Taddei, AR   +9 more
core   +2 more sources

Haemophilus influenzae pneumonia and immunodeficiency in association with thymoma—A presentation of Good's Syndrome

Revista Portuguesa de Pneumologia, 2011
Introduction: Good's Syndrome is a rare cause of immunodeficiency associated with thymoma. Patients with this syndrome are prone to infections with encapsulated microorganisms.
A. Fahim, M. Abuzakouk, S.P. Hart
doaj   +1 more source

A large microRNA cluster on chromosome 19 is a transcriptional hallmark of WHO type A and AB thymomas [PDF]

, 2016
BACKGROUND: Thymomas are one of the most rarely diagnosed malignancies. To better understand its biology and to identify therapeutic targets, we performed next-generation RNA sequencing.
Atale, Rutuja, Badve, Sunil S., Conces, Madison L., Glasscock, Jarret, Hancock, Bradley A., Kesler, Kenneth A., Loehrer, Patrick J., Porter, Ryan F., Radovich, Milan, Schneider, Bryan P., Solzak, Jeffrey P., Zhu, Jin   +11 more
core   +2 more sources

Good's syndrome with diffuse panbronchiolitis as the prominent manifestation: A case and literature review

Respirology Case Reports, 2021
Good's syndrome (GS) is characterized by thymoma combined with adult‐onset immunodeficiency. Diffuse panbronchiolitis (DPB) is a chronic inflammatory airway disease, which predominantly affects East Asians.
Tian Luo, Lile Wang, Daiyan Fu, Ruicheng Hu, Chunchu Kong, Yunrong Chen, Xi Li   +6 more
doaj   +1 more source

Case report: Persistent hypogammaglobulinemia in thymoma-associated myasthenia gravis: the impact of rituximab or Good's syndrome?

Frontiers in Neurology, 2023
IntroductionRituximab (RTX) showed good efficacy and safety for patients with myasthenia gravis. However, the percentage of peripheral CD20+ B cell may be absent for years after low dose of RTX treatment.
Jingru Ren, Jianchun Wang, Ran Liu, Jing Guo, Yan Yao, Jingjing Luo, Hongjun Hao, Feng Gao   +7 more
doaj   +1 more source

Germline TP53 Mutations Causing Diamond–Blackfan Anemia: A French Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Diamond–Blackfan anemia is a rare congenital erythroblastopenia typically caused by mutations in ribosomal protein genes. Recently, gain‐of‐function mutations in TP53 have been identified as a novel cause of Diamond–Blackfan anemia. We report two French patients who both harbored a heterozygous TP53 deletion (NM_000546.5: c.1077delA; p ...
Rafael Moisan, Lydie Da Costa, Ludivine David Nguyen, Heloise Chosseler, Audrey Riquet, Benedicte Bruno, Melissa Barbati   +6 more
wiley   +1 more source

Peripheral B Cell Deficiency and Predisposition to Viral Infections: The Paradigm of Immune Deficiencies

Frontiers in Immunology, 2021
In the era of COVID-19, understanding how our immune system responds to viral infections is more pertinent than ever. Immunodeficiencies with very low or absent B cells offer a valuable model to study the role of humoral immunity against these types of ...
Alexandros Grammatikos, Matthew Donati, Sarah L. Johnston, Mark M. Gompels   +3 more
doaj   +1 more source

The Role of Invasive Procedures in the Treatment of Complicated Gastrointestinal Graft‐Versus‐Host Disease in Pediatric Patients

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Gastrointestinal graft‐versus‐host disease (GI GVHD) following hematopoietic stem cell transplant is typically managed with medical therapy, but surgery and angioembolization may be warranted in selected cases with life‐threatening complications.
Gaia Brunetti, Giorgio Persano, Chiara Grimaldi, Pier Luigi Di Paolo, Carmen Malaspina, Francesco Quagliarella, Valerio Balassone, Anna Chiara Iolanda Contini, Gian Luigi Natali, Rita Alaggio, Ivan Pietro Aloi, Tamara Caldaro, Alessandro Crocoli   +12 more
wiley   +1 more source

Good's Syndrome Presenting With Weaning Failure From Ventilation and Myasthenia Gravis in a Post‐Thymectomy Patient

Respirology Case Reports
Good's syndrome is a rare adult‐onset immunodeficiency associated with thymoma, hypogammaglobulinemia, and cellular immune dysfunction. We report a man in his 50s with a prior thymectomy who presented with recurrent pneumonia, chronic diarrhoea, and ...
Asmita Anilkumar Mehta, Aditya Ashok, Lakshmi Priya Valathara Pradeep, Suchitra Sivadas, George Justin Mothi   +4 more
doaj   +1 more source

Probiotic modulation of the microbiota-gut-brain axis and behaviour in zebrafish [PDF]

, 2016
The gut microbiota plays a crucial role in the bi-directional gut–brain axis, a communication that integrates the gut and central nervous system (CNS) activities.
ACETO, SERENA, AGNISOLA, CLAUDIO, BORRELLI, LUCA, Cryan John F, DE PAOLO, SOFIA, Dinan Timothy G, DIPINETO, LUDOVICO, FIORETTI, ALESSANDRO, MENNA, LUCIA FRANCESCA, Stilling Roman M   +9 more
core   +3 more sources