Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
Determinants of Menstrual Hygiene Practices Among Adolescent Schoolgirls in Saudi Arabia: Implications for Adolescent Health Promotion. [PDF]
Mohamed AI +10 more
europepmc +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Idiopathic esophageal submucosal hematoma after flow diverter stent placement for an unruptured intracranial aneurysm: illustrative case. [PDF]
Shimura S +7 more
europepmc +1 more source
HDAC inhibitors as anticancer drugs: chemical diversity, clinical trials, challenges and perspectives. [PDF]
Abdallah AE.
europepmc +1 more source
AP Model: A Simple Tool to Predict Poor Long-Term PAP Adherence in Obstructive Sleep Apnea. [PDF]
Tawaranurak K, Kongtawee P, Nilrat N.
europepmc +1 more source
Design reality gap issues within an ICT4D project:an assessment of Jigawa State Community Computer Center [PDF]
Good, Alice, Kanya, Rislana Abdulazeez
core
Association between changes in self-esteem and smartphone dependency among Korean adolescents. [PDF]
Ko AJ, Park YS, Kim J, Park EC.
europepmc +1 more source

