Results 91 to 100 of about 9,951,844 (299)

Quality Assurance Status in Iranian Pharmaceutical Industry: A Survey

Journal of Pharmacoeconomics and Pharmaceutical Management, 2015
Introduction: Critical role of quality assurance (QA) system in the pharmaceutical industry could affect on product quality, market development, customer satisfaction, and other element of a successful drug company. Purpose of the Study: The main aim of
Amirreza Hosseinzadeh, Alireza Yektadoost, Hamidreza Hozouri, Rassoul Dinarvand, Abbas Kebriaeezadeh   +4 more
doaj  

A practical and pyrogen-free preparation of 11C-L-methionine in a good manufacturing practice-compliant approach

Journal of Medical Sciences, 2017
Aims: 11C-L-methionine, an amino acid tracer used to delineate certain tumor tissues, has proven to be a prevailing nonfluorodeoxyglucose positron emission tomography (PET) radiopharmaceutical.
Kang-Po Li, Ming-Kuan Hu, Cheng-Yi Cheng, Li-Fan Hsu, Ta-Kai Chou, Chyng-Yann Shiue, Daniel H Shen   +6 more
doaj   +1 more source

Good Manufacturing Practices for Pharmaceuticals A Plan for Total Quality Control from Manufacturer to Consumer

, 2001
An examination of US law and governmental policy affecting domestic and multinational pharmaceutical manufacturing. It recommends pragmatic ways to interpret and comply with FDA current good manufacturing practice (CGMP) regulation and related ...
Willig, Sidney H.
core  

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Generation of Transplantable Retinal Photoreceptors from a Current Good Manufacturing Practice‐Manufactured Human Induced Pluripotent Stem Cell Line

Stem Cells Translational Medicine, 2017
Retinal degeneration often results in the loss of light‐sensing photoreceptors, which leads to permanent vision loss. Generating transplantable retinal photoreceptors using human somatic cell‐derived induced pluripotent stem cells (iPSCs) holds promise ...
Jie Zhu, Joseph Reynolds, Thelma Y. Garcia, Helen Cifuentes, Shereen Chew, Xianmin Zeng, D. Lamba   +6 more
semanticscholar   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

A Good Manufacturing Practice-grade standard protocol for exclusively human mesenchymal stromal cell-derived extracellular vesicles.

Cytotherapy, 2017
BACKGROUND AIMS Extracellular vesicles (EVs) released by mesenchymal stromal cells (MSCs) may contribute to biological processes such as tissue regeneration, immunomodulation and neuroprotection.
K. Pachler, T. Lener, D. Streif, Zsuzsanna A. Dunai, A. Desgeorges, M. Feichtner, Michaela Öller, K. Schallmoser, E. Rohde, M. Gimona   +9 more
semanticscholar   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

A bioreactor system for the manufacture of a genetically modified Plasmodium falciparum blood stage malaria cell bank for use in a clinical trial

Malaria Journal, 2018
Background Although the use of induced blood stage malaria infection has proven to be a valuable tool for testing the efficacy of vaccines and drugs against Plasmodium falciparum, a limiting factor has been the availability of Good Manufacturing Practice
Rebecca Pawliw, Rebecca Farrow, Silvana Sekuloski, Helen Jennings, Julie Healer, Thuan Phuong, Pri Sathe, Cielo Pasay, Krystal Evans, Alan F. Cowman, Louis Schofield, Nanhua Chen, James McCarthy, Katharine Trenholme   +13 more
doaj   +1 more source

Good Manufacturing Practices for Refrigerated Foods

Journal of Food Protection, 1989
Good Manufacturing Practices are essential for the manufacture and distribution of refrigerated foods that are safe from microbiological hazards. A refrigerated foods manufacturer should use a comprehensive program that evaluates, identifies, and then controls potential hazards at every step in the development and manufacturing environment.
openaire   +2 more sources