Results 1 to 10 of about 117,081 (314)

Differences in Expansion Potential of Naive Chimeric Antigen Receptor T Cells from Healthy Donors and Untreated Chronic Lymphocytic Leukemia Patients

open access: yesFrontiers in Immunology, 2018
IntroductionTherapy with chimeric antigen receptor T (CART) cells for hematological malignancies has shown promising results. Effectiveness of CART cells may depend on the ratio of naive (TN) vs.
Jean-Marc Hoffmann   +21 more
doaj   +1 more source

Controlling the Immune Suppressor: Transcription Factors and MicroRNAs Regulating CD73/NT5E

open access: yesFrontiers in Immunology, 2018
The NT5E (CD73) molecule represents an ecto-5′-nucleotidase expressed on the cell surface of various cell types. Hydrolyzing extracellular adenosine monophosphate into adenosine and inorganic phosphate, NT5E performs numerous homeostatic functions in ...
Theresa Kordaß   +3 more
doaj   +1 more source

Current Approaches to the Abnormal Toxicity Test

open access: yesРегуляторные исследования и экспертиза лекарственных средств, 2020
For over 60 years, the Abnormal Toxicity Test (ATT) has been used as an important tool in safety control of some parenteral and veterinary products made from biological materials.
N. P. Neugodova   +4 more
doaj   +1 more source

SV-BR-1-GM, a Clinically Effective GM-CSF-Secreting Breast Cancer Cell Line, Expresses an Immune Signature and Directly Activates CD4+ T Lymphocytes

open access: yesFrontiers in Immunology, 2018
Targeted cancer immunotherapy with irradiated, granulocyte–macrophage colony-stimulating factor (GM-CSF)-secreting, allogeneic cancer cell lines has been an effective approach to reduce tumor burden in several patients. It is generally assumed that to be
Markus D. Lacher   +13 more
doaj   +1 more source

MicroRNAs affecting the susceptibility of melanoma cells to CD8+ T cell‐mediated cytolysis

open access: yesClinical and Translational Medicine, 2023
Background The regulatory functions of microRNAs (miRNAs) in anti‐tumour immunity have been mainly described in immune effector cells. Since little is known about miRNA effects on the susceptibility of target cells during T cell—target cell interaction ...
Antonino A. Pane   +8 more
doaj   +1 more source

HUBUNGAN SIKAP PENJAMAH MAKANAN DENGAN CARA PRODUKSI PANGAN YANG BAIK PADA INDUSTRI RUMAH TANGGA PANGAN DI KAMPUNG KUE SURABAYA
[Correlation of Food Handlers Attitude with Good Manufacturing Practice in the Household Food Industry in Kampung Kue Surabaya]

open access: yesMedia Gizi Indonesia, 2019
The application of Good Manufacturing Practice (GMP) can improve quality of products. Good manufacturing practice aim to make a safe product to be consumed. Attitude of food handlers can affect practice of food handlers on production process. The purpose
Maya Amelia, Annis Adi
doaj   +1 more source

A Hybrid Model of Integrating Sentiment Analysis and Key Market Indicators for IPO Listing Trend Prediction [PDF]

open access: yesInternational Journal of Mathematical, Engineering and Management Sciences
Initial Public Offerings (IPOs) provide great opportunities for companies to grow and expand, and they allow investors to invest their money wisely to get a decent Return on Investment (ROI) in the short term.
Ashish Garg   +2 more
doaj   +1 more source

miR-155-5p drives coordinated tumor and macrophage reprogramming across multiple cancer entities

open access: yesBMC Medicine
Background T cell-based immunotherapies have improved cancer treatment, however their efficacy is frequently limited by tumor-intrinsic resistance mechanisms and by the immune suppressive tumor microenvironment, counteracting tumor specific immune ...
Theresa Kordaß   +9 more
doaj   +1 more source

Simulasi Distribusi Fluks dan Tegangan Generator Magnet Permanen Satu-Fasa Hasil Modifikasi Motor Induksi Rotor Sangkar Satu-Fasa

open access: yesJurnal Elkomika
ABSTRAK Modifikasi motor induksi rotor sangkar satu-fasa (MI) menjadi generator magnet permanen satu-fasa (GMP) memberi manfaat seperti re-use MI bekas serta aplikasinya untuk memanen potensi energi hidro sungai kecil berelevasi rendah.
I MADE WIWIT KASTAWAN, RAHMAT HIDAYAT
doaj   +1 more source

GD2: hopes and challenges for the treatment of pediatric patients with tumors of the central nervous system

open access: yesnpj Precision Oncology
Pediatric Central Nervous System (CNS) tumors are the leading cause of cancer-related death in children, yet effective treatment options remain limited.
Alba Clara Fernández-Rilo   +9 more
doaj   +1 more source

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