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Specificity of the cyclic GMP-bbmding activity and of a cyclic GMP-dependent cyclic GMP phosphodiesterase in Dictyostelium discoideum [PDF]
Molecular and Cellular Endocrinology, 1982 The nucleotide specificity of the cyclic GMP-binding activity in a homogenate of Dictyostelium discoideum was determined by competition of cyclic GMP derivatives with [8-3H]-cyclic GMP for the binding sites. The results indicate that cyclic GMP is bound to the binding proteins by hydrogen bonds at N2H2, N1-H and/or C6 = O, N7, 2(1)-OH and 3(1)-O and ...
T M Konijn +2 more
exaly +6 more sources
Multiple Roles of c-di-GMP Signaling in Bacterial Pathogenesis
Annual Review of Microbiology, 2019 The intracellular signaling molecule cyclic di-GMP (c-di-GMP) regulates the lifestyle of bacteria and controls many key functions and mechanisms. In the case of bacterial pathogens, a wide variety of virulence lifestyle factors have been shown to be ...
Martina Valentini, Alain Filloux
exaly +2 more sources
Journal of Biological Chemistry, 2016 The cyclic di-GMP (c-di-GMP) second messenger represents a signaling system that regulates many bacterial behaviors and is of key importance for driving the lifestyle switch between motile loner cells and biofilm formers.
Martina Valentini, Alain Filloux
exaly +2 more sources
Novel microRNAs modulating ecto-5′-nucleotidase expression
Frontiers in Immunology, 2023 IntroductionThe expression of immune checkpoint molecules (ICMs) by cancer cells is known to counteract tumor-reactive immune responses, thereby promoting tumor immune escape.
Theresa Kordaß +4 more
doaj +1 more source
Nature Communications, 2022 Nucleotide second messengers, such as cAMP and c-di-GMP, regulate many physiological processes in bacteria, including biofilm formation. There is evidence of cross-talk between pathways mediated by c-di-GMP and those mediated by the cAMP receptor protein
Cong Liu +7 more
semanticscholar +1 more source
Controlling biofilm development through cyclic di-GMP signaling
Advances in Experimental Medicine and Biology, 2022 The cyclic di-GMP (c-di-GMP) second messenger represents a signaling system that regulates many bacterial behaviors and is of key importance for driving the lifestyle switch between motile loner cells and biofilm formers.
Soyoung Park, K. Sauer
semanticscholar +1 more source
Journal of Translational Medicine, 2023 Introduction In vitro or in vivo depletion of alloreactive T cells can facilitate haplo-identical hematopoietic stem cell transplantation (HSCT).
E. Wiercinska +11 more
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Autoinducer-2 and bile salts induce c-di-GMP synthesis to repress the T3SS via a T3SS chaperone
Nature Communications, 2022 Cyclic di-GMP (c-di-GMP) transduces extracellular stimuli into intracellular responses, coordinating a plethora of important biological processes. Low levels of c-di-GMP are often associated with highly virulent behavior that depends on the type III ...
Shuyu Li +13 more
semanticscholar +1 more source
KAJIAN PENERAPAN GOOD MANUFACTURING PRACTICES (GMP) PADA PENGOLAHAN KERIPIK PISANG
Agrointek, 2021 The purpose of this study was to examine the application of Good Manufacturing Practices (GMP) in banana chip processing in Konda District. Research data were collected by (a) field studies (observation, interviews, and documentation); and (b) literature
Dhian Herdhiansyah +3 more
doaj +1 more source
Vaccines, 2020 With the emergence of immune checkpoint inhibitors and adoptive T-cell therapies, there is a considerable interest in using personalized autologous dendritic cell (DC) vaccines in combination with T cell-targeting immunotherapies to potentially maximize ...
Caroline Boudousquié +8 more
doaj +1 more source