Results 11 to 20 of about 117,081 (314)

Specificity of the cyclic GMP-bbmding activity and of a cyclic GMP-dependent cyclic GMP phosphodiesterase in Dictyostelium discoideum [PDF]

Molecular and Cellular Endocrinology, 1982
The nucleotide specificity of the cyclic GMP-binding activity in a homogenate of Dictyostelium discoideum was determined by competition of cyclic GMP derivatives with [8-3H]-cyclic GMP for the binding sites. The results indicate that cyclic GMP is bound to the binding proteins by hydrogen bonds at N2H2, N1-H and/or C6 = O, N7, 2(1)-OH and 3(1)-O and ...
Haastert, Peter J.M. van, Walsum, Hans van, Meer, Rob C. van der, Bulgakov, Roman, Konijn, Theo M.   +4 more
openaire   +5 more sources

Novel microRNAs modulating ecto-5′-nucleotidase expression

Frontiers in Immunology, 2023
IntroductionThe expression of immune checkpoint molecules (ICMs) by cancer cells is known to counteract tumor-reactive immune responses, thereby promoting tumor immune escape.
Theresa Kordaß, Theresa Kordaß, Tsu-Yang Chao, Wolfram Osen, Stefan B. Eichmüller   +4 more
doaj   +1 more source

Automatic generation of alloreactivity-reduced donor lymphocytes and hematopoietic stem cells from the same mobilized apheresis product

Journal of Translational Medicine, 2023
Introduction In vitro or in vivo depletion of alloreactive T cells can facilitate haplo-identical hematopoietic stem cell transplantation (HSCT).
E. Wiercinska, P. Quade-Lyssy, C. Hümmer, J. Beifuß, K. Akarkach, C. Poppe, V. Olevska, J. Dzionek, H. Lahnor, A. Bosio, E. Papanikolaou, Halvard Bonig   +11 more
doaj   +1 more source

Development and Optimization of a GMP-Compliant Manufacturing Process for a Personalized Tumor Lysate Dendritic Cell Vaccine

Vaccines, 2020
With the emergence of immune checkpoint inhibitors and adoptive T-cell therapies, there is a considerable interest in using personalized autologous dendritic cell (DC) vaccines in combination with T cell-targeting immunotherapies to potentially maximize ...
Caroline Boudousquié, Valérie Boand, Emilie Lingre, Laeticia Dutoit, Klara Balint, Maxime Danilo, Alexandre Harari, Philippe O. Gannon, Lana E. Kandalaft   +8 more
doaj   +1 more source

KAJIAN PENERAPAN GOOD MANUFACTURING PRACTICES (GMP) PADA PENGOLAHAN KERIPIK PISANG

Agrointek, 2021
The purpose of this study was to examine the application of Good Manufacturing Practices (GMP) in banana chip processing in Konda District. Research data were collected by (a) field studies (observation, interviews, and documentation); and (b) literature
Dhian Herdhiansyah, Gustina Gustina, Andi Besse Patadjai, Asriani asriani   +3 more
doaj   +1 more source

Novel cyclic di-GMP effectors of the YajQ protein family control bacterial virulence [PDF]

, 2014
Bis-(3',5') cyclic di-guanylate (cyclic di-GMP) is a key bacterial second messenger that is implicated in the regulation of many critical processes that include motility, biofilm formation and virulence. Cyclic di-GMP influences diverse functions through
Caly, Delphine L., Joseph Ward (645977), Yvonne McCarthy (109070), Melanie Febrer (185470), Murdoch, Sarah L., Dow, J. Maxwell, Joseph Ward, Robert P. Ryan (108478), Ryan, Robert P., An, Shi Qi, An Shi-qi, Ryan Robert P., Shi-qi An, Robert P Ryan, J. Maxwell Dow (269095), J Maxwell Dow, McCarthy Yvonne, Caly Delphine L., Dow J. Maxwell, An, Shi-qi, Ward Joseph, Delphine L Caly, Yvonne McCarthy, McCarthy, Yvonne, Sarah L Murdoch, Melanie Febrer, Sarah L. Murdoch (645976), Ward, Joseph, Shi-qi An (5661025), Febrer Melanie, Febrer, Melanie, Delphine L. Caly (146386), Murdoch Sarah L.   +32 more
core   +1 more source

Peningkatan Kapasitas dan Mutu Produk Brownies Tempe di Industri Rumah Tangga (IRT) “Browniesta” melalui Introduksi Teknologi Tepat Guna

AgriHealth, 2021
Tempeh had been recognized worldwide as a superfood. In Pengkok Village, Kedawung Sub-district, Sragen Regency, there were several traditional tempeh producers which supply fresh tempeh around Kedawung Sub-district.
Dwi Ishartani, Windi Atmaka, Lia Umi Khasanah, Setyaningrum Ariviani, Siswanti Siswanti   +4 more
doaj   +1 more source

Bi-modal distribution of the second messenger c-di-GMP controls cell fate and asymmetry during the caulobacter cell cycle [PDF]

, 2013
Many bacteria mediate important life-style decisions by varying levels of the second messenger c-di-GMP. Behavioral transitions result from the coordination of complex cellular processes such as motility, surface adherence or the production of virulence ...
Abel, Sören, Bucher, Tabitha, Isabelle Hug (251572), Urs Jenal (37942), Isabelle Hug, Volkhard Kaever, Tabitha Bucher, Pia Abel zur Wiesch (353268), Jenal, U., Sören Abel, Bucher, T., Pia Abel Zur Wiesch, Micaël Nicollier, Micaël Nicollier (454806), Urs Jenal, Volkhard Kaever (152216), Hug, Isabelle, Tabitha Bucher (454805), Sören Abel (454804), Abel Zur Wiesch, P., Kaever, Volkhard, Hug, I., Abel zur Wiesch, Pia, Nicollier, M., Nicollier, Micaël, Abel, S., Jenal, Urs, Kaever, V., Sören Abel, Nicollier M, Abel S, Bucher T, Hug I, Jenal U, Kaever V, Abel Zur Wiesch P   +35 more
core   +2 more sources

Analysis of cyclic di-GMP signaling components in "caulobacter crescentus" behavior and cell cycle control [PDF]

, 2013
Cell cycle progression and polar morphogenesis in Caulobacter crescentus are coordinated by the interplay of multiple proteins in time and space. One major regulatory factor is the second messenger cyclic di-GMP (c-di-GMP) therefore especially the ...
Friedrich, Elvira
core   +1 more source

A PROPOSAL OF PROCESS VALIDATION IN THE IMPLEMENTATION OF GOOD MANUFACTURING PRACTICES IN BRACHYTHERAPY SOURCES PRODUCTION

Brazilian Journal of Radiation Sciences, 2021
New laboratories for brachytherapy sources production are being implemented in our facility at IPEN, in São Paulo. A great challenge implementing a production laboratory is to comply with the Good Manufacturing Practices (GMPs), which involves process ...
Tatyana Spinosa Baptista, Anselmo Feher Feher, Bruna Teiga Rodriguez, Carlos Alberto Zeituni, João Augusto Moura, Maria Elisa Rostelato   +5 more
doaj   +1 more source