Results 11 to 20 of about 101,384 (314)

Specificity of the cyclic GMP-bbmding activity and of a cyclic GMP-dependent cyclic GMP phosphodiesterase in Dictyostelium discoideum [PDF]

open access: yesMolecular and Cellular Endocrinology, 1982
The nucleotide specificity of the cyclic GMP-binding activity in a homogenate of Dictyostelium discoideum was determined by competition of cyclic GMP derivatives with [8-3H]-cyclic GMP for the binding sites. The results indicate that cyclic GMP is bound to the binding proteins by hydrogen bonds at N2H2, N1-H and/or C6 = O, N7, 2(1)-OH and 3(1)-O and ...
Peter J M Van Haastert   +2 more
exaly   +5 more sources

Novel microRNAs modulating ecto-5′-nucleotidase expression

open access: yesFrontiers in Immunology, 2023
IntroductionThe expression of immune checkpoint molecules (ICMs) by cancer cells is known to counteract tumor-reactive immune responses, thereby promoting tumor immune escape.
Theresa Kordaß   +4 more
doaj   +1 more source

Automatic generation of alloreactivity-reduced donor lymphocytes and hematopoietic stem cells from the same mobilized apheresis product

open access: yesJournal of Translational Medicine, 2023
Introduction In vitro or in vivo depletion of alloreactive T cells can facilitate haplo-identical hematopoietic stem cell transplantation (HSCT).
E. Wiercinska   +11 more
doaj   +1 more source

KAJIAN PENERAPAN GOOD MANUFACTURING PRACTICES (GMP) PADA PENGOLAHAN KERIPIK PISANG

open access: yesAgrointek, 2021
The purpose of this study was to examine the application of Good Manufacturing Practices (GMP) in banana chip processing in Konda District. Research data were collected by (a) field studies (observation, interviews, and documentation); and (b) literature
Dhian Herdhiansyah   +3 more
doaj   +1 more source

Development and Optimization of a GMP-Compliant Manufacturing Process for a Personalized Tumor Lysate Dendritic Cell Vaccine

open access: yesVaccines, 2020
With the emergence of immune checkpoint inhibitors and adoptive T-cell therapies, there is a considerable interest in using personalized autologous dendritic cell (DC) vaccines in combination with T cell-targeting immunotherapies to potentially maximize ...
Caroline Boudousquié   +8 more
doaj   +1 more source

Peningkatan Kapasitas dan Mutu Produk Brownies Tempe di Industri Rumah Tangga (IRT) “Browniesta” melalui Introduksi Teknologi Tepat Guna

open access: yesAgriHealth, 2021
Tempeh had been recognized worldwide as a superfood. In Pengkok Village, Kedawung Sub-district, Sragen Regency, there were several traditional tempeh producers which supply fresh tempeh around Kedawung Sub-district.
Dwi Ishartani   +4 more
doaj   +1 more source

Analysis of cyclic di-GMP signaling components in "caulobacter crescentus" behavior and cell cycle control [PDF]

open access: yes, 2013
Cell cycle progression and polar morphogenesis in Caulobacter crescentus are coordinated by the interplay of multiple proteins in time and space. One major regulatory factor is the second messenger cyclic di-GMP (c-di-GMP) therefore especially the ...
Friedrich, Elvira
core   +1 more source

Bi-modal distribution of the second messenger c-di-GMP controls cell fate and asymmetry during the caulobacter cell cycle [PDF]

open access: yes, 2013
Many bacteria mediate important life-style decisions by varying levels of the second messenger c-di-GMP. Behavioral transitions result from the coordination of complex cellular processes such as motility, surface adherence or the production of virulence ...
Abel, Sören   +27 more
core   +1 more source

Procesul de producție al produselor farmaceutice veterinare - Crida Pharm [PDF]

open access: yesMedicamentul Veterinar, 2022
The presentation is a description of CridaPharm, a leading Romanian company where the latest achievements in compliance with European regulations, GMP, and ISO 9001-015 are presented. The stages of the manufacturing process in the six production sections
Gabriel Badic
doaj  

Novel cyclic di-GMP effectors of the YajQ protein family control bacterial virulence [PDF]

open access: yes, 2014
Bis-(3',5') cyclic di-guanylate (cyclic di-GMP) is a key bacterial second messenger that is implicated in the regulation of many critical processes that include motility, biofilm formation and virulence. Cyclic di-GMP influences diverse functions through
Caly, Delphine L.   +32 more
core   +1 more source

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