Results 31 to 40 of about 157,757 (356)
IntroductionTherapy with chimeric antigen receptor T (CART) cells for hematological malignancies has shown promising results. Effectiveness of CART cells may depend on the ratio of naive (TN) vs.
Jean-Marc Hoffmann +21 more
doaj +1 more source
In many bacteria, the biofilm-promoting second messenger c-di-GMP is produced and degraded by multiple diguanylate cyclases (DGC) and phosphodiesterases (PDE), respectively. High target specificity of some of these enzymes has led to theoretical concepts
A. M. Richter +6 more
semanticscholar +1 more source
Activation and polar sequestration of PopA, a c-di-GMP effector protein involved in Caulobacter crescentus cell cycle control [PDF]
When Caulobacter crescentus enters S-phase the replication initiation inhibitor CtrA dynamically positions to the old cell pole to be degraded by the polar ClpXP protease.
Ebbensgaard, Anna Elisabeth +7 more
core +1 more source
Pseudomonas aeruginosa can cause various types of infections and is one of the most ubiquitous antibiotic-resistant pathogens found in healthcare settings.
Ting Li (117885) +8 more
core +1 more source
Pseudomonas aeruginosa can cause various types of infections and is one of the most ubiquitous antibiotic-resistant pathogens found in healthcare settings.
Ting Li (117885) +8 more
core +1 more source
Low cost and open source purification apparatus for GMP [13N]ammonia production [PDF]
Nitrogen-13 labeled ammonia ([13N]NH3) has been used for myocardial perfusion imaging with Positron Emission Tomography for decades. Recent increases to regulatory oversight have led to stricter adherence Good Manufacturing Practice (GMP) to produce this
Farah, Kamar +2 more
core +1 more source
Controlling the Immune Suppressor: Transcription Factors and MicroRNAs Regulating CD73/NT5E
The NT5E (CD73) molecule represents an ecto-5′-nucleotidase expressed on the cell surface of various cell types. Hydrolyzing extracellular adenosine monophosphate into adenosine and inorganic phosphate, NT5E performs numerous homeostatic functions in ...
Theresa Kordaß +3 more
doaj +1 more source
Cyclic-GMP-AMP Is An Endogenous Second Messenger in Innate Immune Signaling by Cytosolic DNA
DNA Sensing Is a (c)GAS DNA is normally localized to the nucleus, and so its cytoplasmic localization sends off alarm bells to the immune system because it indicates that a virus may have entered.
Jiaxi Wu +6 more
semanticscholar +1 more source
Analysis of the c-di-GMP mediated cell fate determination in Caulobacter crescentus [PDF]
Cyclic-di-GMP (c-di-GMP) is a ubiquitous second messenger in bacteria, which has been recognized as a key regulator, antagonistically controlling the transition between motile, planktonic cells and surface attached, multicellular communities.
Abel, Sören
core +1 more source
Pseudomonas aeruginosa is a Gram-negative bacterium that is able to survive and adapt in a multitude of niches as well as thrive within many different hosts. This versatility lies within its large genome of ca. 6 Mbp and a tight control in the expression
Joey Kuok Hoong Yam (6295388) +9 more
core +1 more source

