Results 61 to 70 of about 376,667 (303)

Evaluating the Three Methods of Goodness of Fit Test for Frequency Analysis [PDF]

Journal of Risk Analysis and Crisis Response (JRACR), 2015
In hydrological statistics, the traditional assessment of goodness of fit test is interested in the testing precision to the sample generated from supposed PDF.
Xiankui Zeng, Dong Wang, Jichun Wu
doaj   +1 more source

Nonparametric estimation of the distribution of the autoregressive coefficient from panel random-coefficient AR(1) data [PDF]

, 2016
We discuss nonparametric estimation of the distribution function $G(x)$ of the autoregressive coefficient $a \in (-1,1)$ from a panel of $N$ random-coefficient AR(1) data, each of length $n$, by the empirical distribution function of lag 1 sample ...
Leipus, Remigijus, Philippe, Anne, Pilipauskaitė, Vytautė, Surgailis, Donatas   +3 more
core   +5 more sources

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

Investigating the Factors Affecting Depression By Using Structural Equation Modeling

Galician Medical Journal, 2021
The objective of the research was to study the factors affecting depression in general population. Materials and Methods. A total of 1,291 individuals at the age of 15-68 years participated in this cross-sectional study.
Meryem Firat, Yalçın Kanbay, Burcu Demir Gökmen, Mehmet Utkan, Ayşe Okanli   +4 more
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Goodness-of-fit Testing for Left-truncated Two-parameter Weibull Distributions with Known Truncation Point

Austrian Journal of Statistics, 2016
The left-truncated Weibull distribution is used in life-time analysis, it has many applications ranging from financial market analysis and insurance claims to the earthquake inter-arrival times.
Ayse KIZILERSU, Markus Kreer, Anthony W. Thomas   +2 more
doaj   +1 more source

Applicability of Item Response Theory to the Korean Nurses' Licensing Examination [PDF]

Journal of Educational Evaluation for Health Professions, 2005
To test the applicability of item response theory (IRT) to the Korean Nurses' Licensing Examination (KNLE), item analysis was performed after testing the unidimensionality and goodness-of-fit.
Geum-Hee Jeong, Mi Kyoung Yim
doaj   +1 more source

Goodness-of-Fit Tests in Nonparametric Regression [PDF]

SSRN Electronic Journal, 2006
AMS classifications: 62G08, 62G10, 62G20, 62G30; 60F17.
Einmahl, J.H.J., Keilegom, I. van
openaire   +8 more sources