Results 101 to 110 of about 369,312 (287)
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Pearson's goodness-of-fit tests for sparse distributions. [PDF]
J Appl Stat, 2023 Chang S, Li D, Qi Y.
europepmc +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
A note on goodness of fit test using moments
Statistica, 2007 The purpose of this article is to introduce a general moment-based approach to derive formal goodness of fit tests of a parametric family. We show that, in general, an approximate normal test or a chi-squared test can be derived by exploring the moment ...
Alex Papadopoulos, Gang Li
doaj +1 more source
Bayesian estimation of extropy and goodness of fit tests. [PDF]
J Appl Stat, 2022 Al-Labadi L, Berry S.
europepmc +1 more source
, 2012 The process comparing the empirical cumulative distribution function of the sample with a parametric estimate of the cumulative distribution function is known as the empirical process with estimated parameters and has been extensively employed in the ...
Kojadinovic, Ivan, Yan, Jun
core +3 more sources
Targeting p38α in cancer: challenges, opportunities, and emerging strategies
Molecular Oncology, EarlyView.p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley +1 more source
Informative Features for Model Comparison [PDF]
, 2018 Given two candidate models, and a set of target observations, we address the problem of measuring the relative goodness of fit of the two models. We propose two new statistical tests which are nonparametric, computationally efficient (runtime complexity ...
Gretton, Arthur +5 more
core +1 more source
FEBS Open Bio, EarlyView.This study addressed how a senior research thesis is perceived by undergraduate students. It assessed students' perception of research skills, epistemological beliefs, and career goals in Biochemistry (science) and BDC (science‐business) students. Completing a thesis improved confidence in research skills, resilience, scientific identity, closed gender‐
Celeste Suart +4 more
wiley +1 more source
The Q-Lindley Distribution: Goodness-of-Fit Tests, Modeling, Inference, and Applications
Journal of Statistical Theory and Applications (JSTA)This paper introduces the Q-Lindley distribution (QLD), a new one-parameter model for lifetime and reliability data derived from the affine exponential family. We derive its main statistical properties and estimate the parameter using maximum likelihood.
Noureddine Saaidia +2 more
doaj +1 more source