Results 101 to 110 of about 176,715 (305)
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Robust correlation coefficient goodness-of-fit test for the Gumbel distribution
Background & Aim: A single outlier can even have a large disturbing effect on a classical statistical method that is optimal under the classical assumptions.
Abbas Mahdavi
doaj
The question of how to choose a copula model that best fits a given dataset is a predominant limitation of the copula approach, and the present study aims to investigate the techniques of goodness-of-fit tests for multi-dimensional copulas. A goodness-of-
Ming-wei Ma +4 more
doaj +1 more source
A goodness-of-fit test based on neural network sieve estimators. [PDF]
Shen X, Jiang C, Sakhanenko L, Lu Q.
europepmc +1 more source
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley +1 more source
Asymptotic properties of a goodness-of-fit test based on maximum correlations [PDF]
We study the efficiency properties of the goodness-of-fit test based on the Qn statistic introduced in Fortiana and Grané (2003) using the concepts of Bahadur asymptotic relative efficiency and Bahadur asymptotic optimality.
Aurea Grane, Anna V. Tchirina
core
Why human connection is the true metric of research success
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan +3 more
wiley +1 more source
Goodness-of-fit tests for the Compound Rayleigh distribution with application to real data
An important problem in statistics is to obtain information about the form of the population from which the sample is drawn. Goodness of fit (GOF) tests is employed to determine how well the observed sample data “fits” some proposed model. The well known
Majdah M. Badr
doaj +1 more source
Goodness-of-fit test for exponentiality based on spacings for general progressive Type-II censored data. [PDF]
Qin X, Yu J, Gui W.
europepmc +1 more source
Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee +3 more
wiley +1 more source

