Results 51 to 60 of about 14,284 (259)

A Repertoire of Major Genes From Crop Wild Relatives for Breeding Disease‐Resistant Wheat, Rice, Maize, Soybean and Cotton Crops

Plant Breeding, EarlyView.
ABSTRACT Global food demand is predicted to rise anywhere from 59% to 98% by 2050 because of increasing population. However, the continued depletion of natural resources and increasing biotic and abiotic stresses will continue to pose significant threats to global food security in coming years.
Memoona Khalid, Hafiz Mamoon Rehman, Tsz‐Yan Cheung, Shakeel Ahmed, Ting Fung Chan, Hon‐Ming Lam   +5 more
wiley   +1 more source

Genomics and metabolic responses reveal the effect of Candida tropicalis ZD-3 on the degradation of Gossypol

Ecotoxicology and Environmental Safety
Cottonseed meal is widely used as an alternative source of protein in the animal feed industry. However, the presence of toxic gossypol limits its use in livestock production.
Li Zhang, Xiaolong Yang, Rongzheng Huang, Shanshan Nan, Junli Niu, Cunxi Nie, Cheng Chen, Wenju Zhang   +7 more
doaj   +1 more source

Gossypol Inhibits Non-small Cell Lung Cancer Cells Proliferation by Targeting EGFRL858R/T790M

Frontiers in Pharmacology, 2018
Background: Overexpression of epidermal growth factor receptor (EGFR) has been reported to be implicated in the pathogenesis of non-small cell lung cancer (NSCLC).
Yuwei Wang, Huanling Lai, Xingxing Fan, Lianxiang Luo, Fugang Duan, Zebo Jiang, Qianqian Wang, Elaine Lai Han Leung, Elaine Lai Han Leung, Elaine Lai Han Leung, Liang Liu, Xiaojun Yao   +11 more
doaj   +1 more source

Mining Potential Therapeutic Targets for T Cell Exhaustion in Osteoarthritis by Integrating Mendelian Randomization and Single‐Cell Sequencing

The FASEB Journal, Volume 40, Issue 2, 31 January 2026.
This study conducted an integrated analysis using multi‐source data, with specific data sources including the GEO database (encompassing datasets GSE55235, GSE55457, and GSE152805), literature‐mined gene sets, and the IEU OpenGWAS database (dataset ebi‐a‐GCST005814).
Jiahong Li, Yi Ye, Yan Zhang, Wei Fang, Fei Lan, Qian Yang, Lun Wan, Jiang Hu, Chengwei Xiao, Kun Zhang   +9 more
wiley   +1 more source

Gossypol: phytoalexin of cotton [PDF]

Science China Life Sciences, 2016
Sesquiterpenoids are a class of 15-carbon secondary metabolites that play diverse roles in plant adaptation to environment. Cotton plants accumulate a large amount of sesquiterpene aldehydes (including gossypol) as phytoalexins against pathogens and herbivores. They are stored in pigment glands of aerial organs and in epidermal layers of roots. Several
Tian, Xiu, Ruan, Juxin, Huang, Jinquan, Fang, Xin, Mao, Yingbo, Wang, Lingjian, Chen, Xiaoya, Yang, Changqing   +7 more
openaire   +2 more sources

Engineering Gossypol‐Free Cottonseeds for Future Global Food Security and Agricultural Sustainability

Food Frontiers, Volume 7, Issue 1, January 2026.
This study depicting the role of transcriptomics, RNA interference (RNAi), and CRISPR/Cas9 technologies in the breeding of glandless cottonseed and glanded cotton tissues. This approach demonstrates the potential of cotton as a dual‐purpose crop, serving both the fiber industry and as a sustainable food and feed source.
Teame Gereziher Mehari, Muhammad Yousaf Shani, Junfeng Tang, Hui Fang, Muhammad Jawad Umer, Fang Liu, Kai Wang, Dengbing Yao, Muhammad K. R. Khan, Baohua Wang   +9 more
wiley   +1 more source

Effect of Achillea santolina on mice spermatogenesis [PDF]

, 2004
Achillea santolina, a common variety of Achillea in Golestan province of Iran has been used in traditional medicine for its anti - inflammatory properties.
Azadbakht, M., Azarhoush, R., Golalipour, M.J., Khori, V., Nayebpour, M.   +4 more
core   +1 more source

Biodegradation of Gossypol by Aspergillus terreus-YJ01

Microorganisms, 2023
Gossypol, generally found in the roots, stems, leaves, and, especially, the seeds of cotton plants, is highly toxic to animals and humans, which inhibits the use of cotton stalks as a feed resource.
Yao Jiang, Xinyue Du, Qianqian Xu, Chunhua Yin, Haiyang Zhang, Yang Liu, Xiaolu Liu, Hai Yan   +7 more
doaj   +1 more source

(-)-Gossypol enhances epirubicin's anti-tumor effects on hepatocellular carcinoma in vitro via down-regulating X-linked inhibitor of apoptosis protein

陆军军医大学学报, 2022
Objective To investigate mechanism and effect on (-)-gossypol enhancing epirubicin killing hepatocellular carcinoma (HCC) cells. Methods HCC cells (Hep 3B and HuH7) were divided into 8 groups: control, (-)-gossypol, epirubicin, combination, si-control ...
JIANG Wenbin, SUN Liangbo, DU Yexiang, XIAO Yunhua   +3 more
doaj   +1 more source

The Quest for Functional Ingredients for Sustainable Aquaculture Feeds in Sub‐Saharan Africa

Aquaculture Nutrition, Volume 2026, Issue 1, 2026.
The aquaculture sector plays a key role in ensuring food and nutritional security as well as fostering economic growth in sub‐Saharan Africa (SSA). However, as the sector continues to grow, its future faces economic, environmental, and sustainability challenges.
Arnold Ebuka Irabor, Rodrigue Yossa, Nurul Ahmad Fatan, Matthew A. G. Owen, Parisa Norouzitallab, Kartik Baruah, Arkadios Dimitroglou   +6 more
wiley   +1 more source