Results 141 to 150 of about 64,826 (258)
ABSTRACT Introduction First metatarsophalangeal (MTP) joint osteoarthritis (OA) is a common and disabling condition that causes substantial pain and impairs quality of life. Cushioned insoles have the potential to lower plantar pressures beneath the hallux and possibly reduce pain, but their clinical effectiveness has not been investigated.
Kade L. Paterson +6 more
wiley +1 more source
Peripheral blood circMAN1A2 as a novel diagnostic biomarker for gout: integrated transcriptomic analysis and clinical validation. [PDF]
Guo W +7 more
europepmc +1 more source
Gouty stone of the left bulbar conjunctiva: Report of a rare case
Benwei Cheng +3 more
doaj +1 more source
ABSTRACT Background A 34‐year‐old man presented to our primary care clinic with persistent pain and swelling of the right first metatarsophalangeal joint lasting 3 months. A previous clinic had suspected gout based on hyperuricemia, but urate‐lowering therapy was repeatedly withheld because of ongoing inflammation, resulting in prolonged symptoms ...
Takayuki Yamada
wiley +1 more source
Advances in post-translational and epigenetic modification of hyperuricemia-to-gout progression: mechanisms and therapeutic targets. [PDF]
Fu W +9 more
europepmc +1 more source
Intelligent design of artificial biocatalyst for biomedical diseases
This review summarizes recent advances in the intelligent design of artificial biocatalysts for biomedical diseases. By leveraging tailored design strategies, including environment‐responsive engineering and rational/artificial intelligence‐aided optimization, these biocatalysts enable precise modulation of pathological microenvironments and targeted ...
Lijie Zhang +3 more
wiley +1 more source
Preinfusion Glucocorticoid Reduction and Elimination in Patients With Uncontrolled Gout on Pegloticase and Methotrexate: A Case Series. [PDF]
Albert J +3 more
europepmc +1 more source
ABSTRACT Objective To explore the individual, interpersonal, community, organisational, and policy‐level factors that influence physical activity among people with arthritis in England, using the Social Ecological Model as the analytical framework. Study Design Qualitative research.
Justin Webb, Heather Allison
wiley +1 more source
The gut-joint axis in gout: microbial outer membrane vesicles and m<sup>6</sup>A-mediated metabolic-epigenetic coupling from acute flare to chronicity. [PDF]
Qi Y, Bai J, Liu D, Wang S.
europepmc +1 more source
Obesity and hypertension co‐exist and share molecular mechanisms in terms of dietary therapy, modulated by food bioactive constituents. ABSTRACT Obesity and hypertension are among the most pressing global public health challenges. They frequently co‐exist, with obesity‐related hypertension accounting for an estimated 75% of the hypertension burden ...
Samuel Oluwasegun Maccarthy +3 more
wiley +1 more source

