Results 161 to 170 of about 139,634 (224)

Leading the Way: Multi‐Drug Resistance Protein (MDR1) and Clinical Pharmacology—Commentary on Kim et al.

open access: yesClinical Pharmacology &Therapeutics, Volume 117, Issue 6, Page 1562-1576, June 2025.
Over the last three decades, transporters have become increasingly recognized for their important roles in clinical pharmacology. As gatekeepers of drug absorption, disposition and targeting, transporters in the intestine, liver, kidney and blood brain barrier have been the subject of many clinical pharmacology studies. A seminal work published in 2001
Kathleen M. Giacomini
wiley   +1 more source

Decreased endogenous nitric oxide production in acute decompensated heart failure with a reduced ejection fraction

open access: yesESC Heart Failure, Volume 12, Issue 3, Page 2278-2286, June 2025.
Abstract Aims Heart failure represents a substantial burden to both patients and healthcare systems worldwide. Nitric oxide (NO) dysregulation may play a key role in patients transitioning from chronic to acute heart failure with a reduced ejection fraction (HFrEF). Plasma nitrite (NO2−) is highly reflective of local nitric oxide production and has not
Roman Falls   +3 more
wiley   +1 more source

Footwear Toe‐Box Shape and Medial Forefoot Pressures in Women With Hallux Valgus

open access: yesJournal of Foot and Ankle Research, Volume 18, Issue 2, June 2025.
ABSTRACT Background Narrow fitting footwear is a modifiable risk factor for the development of hallux valgus (HV). Despite this, the pressure that footwear exerts at the medial forefoot has not been fully evaluated in people with HV. Therefore, the objective of this study was to determine whether the toe box of footwear habitually worn by women with HV
Katrina J. Bajraszewski   +9 more
wiley   +1 more source

Public knowledge and awareness of gout among adults in Jeddah, Saudi Arabia: A cross-sectional study. [PDF]

open access: yesMedicine (Baltimore)
Alzain MA   +9 more
europepmc   +1 more source

Impact of Working From Home on the Psychological Well‐Being of 365 European Patients With Rheumatic Diseases During COVID‐19 Pandemic. Results of the REUMAVID Study

open access: yesMusculoskeletal Care, Volume 23, Issue 2, June 2025.
ABSTRACT Objective To evaluate the impact of home working on the psychological well‐being of European patients with Rheumatic and Musculoskeletal Diseases (RMDs) during the COVID‐19 pandemic. Methods REUMAVID is a cross‐sectional study that collected data through an online survey in seven European countries during the COVID‐19 pandemic: Phase 1 (April ...
Marco Garrido‐Cumbrera   +4 more
wiley   +1 more source

The role of high large unstained cell percentages in ongoing inflammation in the intercritical gout. [PDF]

open access: yesJt Dis Relat Surg
Rezan Koçak Ulucaköy RKURKU   +9 more
europepmc   +1 more source

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