Osteoarthritis: Epidemiology, Diagnosis, and Treatment
Osteoarthritis (OA) is a multifactorial degenerative joint disease and a leading cause of disability worldwide. This graphical abstract summarizes the epidemiology, diagnostic strategies, and therapeutic approaches of OA. OA development is driven by aging, metabolic dysregulation, and mechanical stress, leading to progressive joint degeneration ...
Qin Ru +7 more
wiley +1 more source
The fixed oil from Sanguisorba minor Scop. seeds exhibits low antioxidant activity in DPPH• and ABTS+ assays, while it demonstrates high antimicrobial activity, with MBC (22.5 ‐ 45 μL/mL) and MFC (5.625 ‐ 11.25 μL/mL) values. Linoleic acid (43.26%), α‐linolenic acid (25.31%), and oleic acid (20.73%), identified by GC‐MS as the main fatty acids, are ...
Zehra Torun +3 more
wiley +1 more source
Gouty stone of the left bulbar conjunctiva: Report of a rare case
Benwei Cheng +3 more
doaj +1 more source
Peripheral blood circMAN1A2 as a novel diagnostic biomarker for gout: integrated transcriptomic analysis and clinical validation. [PDF]
Guo W +7 more
europepmc +1 more source
Advances in the management of gout: Critical appraisal of febuxostat in the control of hyperuricemia
Lada Beara-Lasic1,3, Michael H Pillinger2,3, David S Goldfarb1,31Divisions of Nephrology and 2Rheumatology, Department of Medicine, NYU Langone Medical Center, New York, NY, USA; 3Department of Medicine, New York Harbor VA Health Care System, New York ...
David S Goldfarb +2 more
core
Advances in post-translational and epigenetic modification of hyperuricemia-to-gout progression: mechanisms and therapeutic targets. [PDF]
Fu W +9 more
europepmc +1 more source
ABSTRACT Aims To evaluate the associations between semaglutide initiation and long‐term skeletal outcomes in people with obesity, stratified by type 2 diabetes (T2D) status, using target trial emulation. Materials and Methods This retrospective cohort study used the TriNetX federated electronic health record network.
Yu‐Nan Huang +8 more
wiley +1 more source
Preinfusion Glucocorticoid Reduction and Elimination in Patients With Uncontrolled Gout on Pegloticase and Methotrexate: A Case Series. [PDF]
Albert J +3 more
europepmc +1 more source
ABSTRACT Background Eating disorders (ED) and psychosis/psychotic‐spectrum disorders (PSD) have overlapping symptoms and may co‐occur in a variety of presentations. Due to its debilitating and life‐threatening risk, it is important for clinicians to be aware of how catatonia may present within these co‐occurrences.
Rosiel Elwyn
wiley +1 more source
The gut-joint axis in gout: microbial outer membrane vesicles and m<sup>6</sup>A-mediated metabolic-epigenetic coupling from acute flare to chronicity. [PDF]
Qi Y, Bai J, Liu D, Wang S.
europepmc +1 more source

