Results 61 to 70 of about 46,765 (290)
Advanced Science, EarlyView.Spatial transcriptomics reveals a remodeled fibroblast‐immune microenvironment in the temporomandibular joint (TMJ) during arthritis. By combining seqFISH with genetic mouse models, this study uncovers TMJ spatial cell atalas, macrophage‐fibroblast crosstalk, and cytokine signaling pathways driving TMJ inflammation and pain.
Ziying Lin +10 more
wiley +1 more source
Научно-практическая ревматология, 2008 Objective. To reveal short course of glucocorticoid (GC) therapy efficacy predictors in pts with gout arthritis. Material and methods. 59 pts with tophaceous gout (crystal-verified diagnosis) and arthritis of three and more joints lasting more than a ...
A A Fedorova +3 more
doaj +1 more source
Risk Factors in the Incidence of Gouty Arthritis in Masohi Town, Central Maluku Regency in 2010 [PDF]
, 2012 The gouty arthritis incidence rate in Masohi Townof Central Maluku Regency is 54 people based on the data from the general hospital in Masohi. The aim of study was to find out the risk factor in the incidence of gouty arthritis in Masohi Town of ...
Amiruddin, R. (Ridwan) +2 more
core +1 more source
Establishment of a novel cynomolgus monkey model of hyperuricemia
Animal Models and Experimental Medicine, EarlyView.We established a novel hyperuricemia model in cynomolgus monkeys (A) via oral administration of potassium oxonate, hydrochlorothiazide, and adenine mixed in fruits and vegetables. This model (B) targets uric acid synthesis and enzymatic degradation, and (C) regulates renal and intestinal excretion, thereby stably elevating serum uric acid and serving ...
Ji‐Wei Wang +12 more
wiley +1 more source
Frontiers in EndocrinologyBackgroundGouty arthritis is a common inflammatory arthritis. The recurrent gout attacks severely damage the joint’s function, lead to bone erosion, and affect bone metabolism.
Yixuan Li +8 more
doaj +1 more source
Infected nasal gout tophus: A case report
Clinical Case Reports, 2022 Gout is a common form of inflammatory arthritis, characterized by the deposition of monosodium urate crystals. If chronically present and not adequately treated by serum urate reducers, gout tophi can develop at various locations.
Gill Verstappen +4 more
doaj +1 more source
Clinical–Radiological Spectrum of Cerebral Amyloid Angiopathy‐Related Inflammation
Annals of Neurology, EarlyView.Objective To identify clinical and radiological features of cerebral amyloid angiopathy‐related inflammation (CAA‐ri), and compare these features with those of sporadic CAA, to improve the understanding, diagnosis, and clinical care of CAA‐ri. Methods We retrospectively reviewed routine clinical data from 37 patients with CAA‐ri and 158 patients with ...
Larysa Panteleienko +9 more
wiley +1 more source
Back Again to the Future: A New Era for Cerebroprotection
Annals of Neurology, EarlyView.Cerebroprotection is a fresh framework for designing neurological therapy that targets glia and vascular cells, in addition to neurons. In the future, successful cerebroprotection will involve targeting all elements of the neurovascular unit. Preclinical trials must include functional outcomes, as well as lesion morphometry.
Patrick Lyden
wiley +1 more source
Some historical remarks on microcrystalline arthritis (gout and chondrocalcinosis)
Reumatismo, 2012 The history of microcrystalline arthritis only began in 1961 when Daniel McCarty and Joseph Lee Hollander demonstrated the presence of sodium monourate crystals in the synovial fluid of gouty patients. However, gout is a historical disease, thanks to the
G. Pasero, P. Marson
doaj +1 more source
Gout gone awry: The importance of proper diagnosis
Clinical Case Reports, 2021 Gout is the best‐known type of arthritis with a prevalence of 1%–3% in the western world (Therapeutic Advances in Musculoskeletal Disease, 6, 2014 and 131; Journal of Advanced Research, 8, 2017 and 495).
Sophia Tessema +2 more
doaj +1 more source