Results 71 to 80 of about 9,244 (205)

Effect of foot immersion and neck cooling on renal, intestinal, immune and inflammatory markers in older adults exposed to extreme heat

Experimental Physiology, EarlyView.
Abstract Older adults with reduced thermoregulatory capabilities are increasingly at risk of heat‐related pathophysiological outcomes (e.g., acute kidney injury, heatstroke) due to increasingly frequent, prolonged and intense heatwaves. Foot immersion and neck cooling have been proposed as practical, non‐electrical cooling strategies for protecting ...
Thomas McCarthy, Ben J. Lee, James J. McCormick, Kelli E. King, Emma R. McCourt, Luana C. Main, Robert D. Meade, Glen P. Kenny   +7 more
wiley   +1 more source

Haglund Deformity and Plantar Calcaneal Spur in Insertional Achilles Tendinopathy: Prevalence, Coexistence, and Radiographic Characteristics

Journal of Foot and Ankle Research, Volume 19, Issue 4, December 2026.
ABSTRACT Background Insertional Achilles tendinopathy (IAT) is a common cause of posterior heel pain and has been associated with several osseous abnormalities around the calcaneus. Although Haglund deformity and plantar calcaneal spur (PCS) have each been linked to IAT, their coexistence and radiographic characteristics have not been comprehensively ...
İbrahim Halil Dadir
wiley   +1 more source

Impact of COVID‐19 Restrictions on Estimating Causal Effects: Fluoroquinolones and Tendon Rupture

Pharmacoepidemiology and Drug Safety, Volume 35, Issue 11, November 2026.
ABSTRACT Purpose The COVID‐19 pandemic disrupted healthcare services, potentially affecting causal effect estimation using real‐world data. As a case study, we replicated a cohort study using Clinical Practice Research Datalink Aurum to evaluate whether pandemic‐related disruptions influenced the measured association between fluoroquinolone use and ...
Angel Y. S. Wong, Jeremy P. Brown, John Tazare, Marleen Bokern, Elizabeth Williamson, Jonathan Bartlett, Charlotte Warren‐Gash, Ian Douglas   +7 more
wiley   +1 more source

Upadacitinib sustained-release tablets for the treatment of chronic refractory gouty arthritis: a case report and literature review

Frontiers in Medicine
BackgroundGouty arthritis (GA) is a crystal-related joint disease caused by the deposition of monosodium urate (MSU) crystals, directly associated with hyperuricemia resulting from purine metabolism disorder and/or reduced uric acid excretion.
Lishi Yu, Weidong Huang, Honghua Lv, Lie Jin, Wenhui Lei   +4 more
doaj   +1 more source

Continuous Intravenous Acyclovir as Outpatient Parenteral Antimicrobial Therapy for HSV and VZV Neurological Infections: A Case Series With Pharmacokinetic and Cost Evaluation, and Review of Literature

Reviews in Medical Virology, Volume 36, Issue 6, November 2026.
ABSTRACT Varicella zoster virus (VZV) and herpes simplex virus (HSV) are major causes of viral meningitis and encephalitis. Standard intermittent intravenous acyclovir requires hospitalisation, reducing patient comfort and prolonging admissions. Continuous infusion may maintain therapeutic plasma and cerebrospinal fluid (CSF) concentrations while ...
Irene G. Manders, Eline L. van Tuinen, Martijn Weisfelt, Marco Goeijenbier, Jayant S. Kalpoe, Steven F. L. van Lelyveld, Eric C. M. van Gorp, Ken Ho Hua   +7 more
wiley   +1 more source

Economic Burden of Overweight and Obesity in Sweden: Current Estimates and Future Projections

Diabetes, Obesity and Metabolism, Volume 28, Issue 11, Page 9871-9879, November 2026.
ABSTRACT Aims Overweight and obesity are major public health challenges and well‐established risk factors for cardiovascular disease, cancer and premature mortality. We estimated the economic burden of overweight and obesity in Sweden in 2023 and projected the future economic burden in 2040 under alternative scenarios of increasing prevalence ...
Adam Fridhammar, Jovanna Dahlgren, Marije Galavazi, Lena Hjelm, Jonatan Dereke, Katarina Steen Carlsson   +5 more
wiley   +1 more source

ETHORICOXIB IN THE TREATMENT OF RHEUMATIC DISEASES

Современная ревматология, 2010
Ethoricoxib is a new-generation selective COX-2 inhibitor. It has been recently licensed in Russia for the treatment of osteoarthrosis (OA), rheumatoid arthritis (RA), ankylosing spondylitis (AS), and acute gouty arthritis.
Yu A Olyunin, Yu A Olyunin
doaj   +1 more source

Initiation of SGLT2 Inhibitors Versus DPP‐4 Inhibitors in Metformin Users and Risk of Incident Depression: A Nationwide, Claims‐Based Active‐Comparator New‐User Study

Diabetes, Obesity and Metabolism, Volume 28, Issue 11, Page 10765-10779, November 2026.
ABSTRACT Aims To examine the association between initiation of sodium‐glucose cotransporter‐2 (SGLT2) inhibitors and risk of incident depression compared with dipeptidyl peptidase‐4 (DPP‐4) inhibitors among adults with newly diagnosed Type 2 diabetes receiving metformin.
Sangwoo Park, Seogsong Jeong, Hye Jun Kim, Dae Ho Lee, Soo Jung Choi, Sang Min Park   +5 more
wiley   +1 more source

Alterations in articular cartilage frictional properties in the setting of acute gouty arthritis.

PLoS ONE
The tribological behaviour of articular cartilage plays a key role in joint motion; however, there is a gap in research on the effect of hyperuricemic joint fluid on cartilage friction behaviour in acute gouty arthritis.
Pai Zheng, Xueer Zhang, Chengcheng Feng, Yuhong Yu, Guangwei Che, Zhihong Cao, Li Tian, Yong Huang   +7 more
doaj   +1 more source

Cell-based in vitro hemoassay for evaluation of NLRP3-inflammasome activity

Медицинская иммунология
Currently, gouty arthritis is considered as a polygenic multifactorial autoinflammatory disease caused by activation of the NOD (nucleotide-binding domain) -like protein receptor 3 inflammasome NLRP3.
N. K. Ossina, L. T. Volova, P. A. Lebedev, I. A. Shafieva, E. I. Pugachev, S. A. Goncharenko, S. I. Kuznetsov, O. A. Gusyakova, G. N. Svetlova   +8 more
doaj   +1 more source