Results 51 to 60 of about 4,999,446 (322)
Ecology and Society, 2016 Successful natural resource management is dependent on effective knowledge exchange and utilization. Local/traditional/indigenous knowledge derived from place-based experience and scientific knowledge generated by systematic inquiry are the most commonly
Forrest Fleischman, David D. Briske
doaj +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Misogyny in Brazilian Federal Government Agencies for Science and High-Education
Anais da Academia Brasileira de Ciências, 2021 The transformation of women’s role in society has been systematically studied. Numerous authors point out that among the factors of extreme relevance to this fact, the main is the increased presence of women in the formal job market.
ROBERTA PEIXOTO ARÊAS DA SILVA +4 more
doaj +1 more source
Investigation of eGovernment Services and Alignment between Business and Information Systems [PDF]
, 2019 Inhabitant’s implementation of eGovernment services is a key objective for the Government of developed and developing countries. However, to improve the eGovernment services it is important for any Government to align all stakeholders so that the needs ...
Alfadhel, Sulaiman +2 more
core +2 more sources
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Critique [of Racism and the Canadian State by Daiva K. Stasiulis] [PDF]
, 1985 Stasiulis\u27s two-part essay offers a critique of the policies on immigration and racism pursued by the Canadian government during the past decade or so.
Hoglund, A. William
core +1 more source
Proceedings of the National Academy of Sciences of the United States of America, 2019 Significance As protected areas (PAs) are a leading conservation strategy, understanding what conditions affect their impacts is critical. We expect different government agencies to vary in their PA locations and management. We offer a test of whether PA
Diego Herrera, A. Pfaff, J. Robalino
semanticscholar +1 more source
FEBS Letters, EarlyView.Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
40 Years of FOIA, 20 Years of Delay: Oldest Pending Freedom of Information Requests Date Back to the 1980s [PDF]
, 2007 Presents findings from the Knight Open Government Survey, which surveys government offices and agencies on the status of their public information requests, and finds that extensive backlogs ...
Catherine Nielsen
core