Results 61 to 70 of about 4,999,446 (322)
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Performance Evaluation of the Government Agencies of Kazakhstan
NISPAcee Journal of Public Administration and Policy, 2018 Performance evaluation of the government agencies seems to be one of the most important issues in modern public administration. The countries with developed economies introduced various performance evaluation models.
G. Suleimenova +3 more
semanticscholar +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
RELATIONSHIPS BETWEEN DISTRICT COUNCILS OF SOUTH-EASTERN RUSSIA AND THE GOVERNMENT IN 1913-1917
Гуманитарные и юридические исследования, 2021 The article discusses the relationships between district councils of south-eastern Russia and the government in 1913 - 1917. The author examines the mission, forms and types of activities of local institutions, as well as the specifics of their ...
O. Adamenko
doaj
Modernisation, managerialism and the culture wars: the reshaping of the local welfare state in England [PDF]
, 2004 The story of local government over the last few decades is often summarised in the assertion that there has been a move away from institutional authority embodied in the structures of councils towards more complex networks of local governance ...
Cochrane, Allan
core +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Disability Employment Policies and Practices in U.S. Federal Government Agencies [PDF]
, 1999 A survey of U.S. Federal agencies was initiated by the Presidential Task Force on Employment of Adults with Disabilities, and 403 representatives of U.S.
Bruyere, Susanne M, Horne, Richard L
core +1 more source
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
Indian Journal of Community Medicine, 1996 Research Question: What is the level of Public awareness on AIDS in a rural community and to what extent the government and non-government agencies have played their role in creating the awareness?
Balagnesh G +3 more
doaj
Design and development of wisdom-based organization model in government agencies [PDF]
مدیریت دولتی, 2015 The importance of wisdom in managerial and organizational issues is growing. Wisdom, in addition to being the rational and moral judgment, is the most important success factor for organization.
Morteza Moradi
doaj +1 more source