Synchronised firing patterns in a random network of adaptive exponential integrate-and-fire neuron model [PDF]
Acknowledgements This study was possible by partial financial support from the following Brazilian government agencies: CNPq, CAPES, and FAPESP (2011/19296-1 and 2015/07311-7).
Baptista, M.S. +7 more
core +1 more source
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Insourcing Functions Performed by Federal Contractors: Legal Issues [PDF]
[Excerpt] While agencies are prohibited by federal law and policy from contracting out functions that are “inherently governmental,” other functions could potentially be contracted out.
Manuel, Kate M, Maskell, Jack
core +2 more sources
TQM-ing OMB: Or Why Regulatory Review Under Executive Order 12,291 Works Poorly and What President Clinton Should Do About It [PDF]
Reflections are presented on how Pres Clinton should improve the deeply troubled relationship between the OMB and other government agencies.
Eklund, Britta +2 more
core +3 more sources
Targeting p38α in cancer: challenges, opportunities, and emerging strategies
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley +1 more source
Feasibility of the Implementation of Activity-Based Costing (ABC) in Operational Budgeting of Government Agencies (A Case Study of Government Agencies of Isfahan Province) [PDF]
Introduction: This research investigated the factors affecting implementation of activity based costing (ABC) in operational budgeting of government agencies in Isfahan province.
D. Foroghi +2 more
doaj
Determinants of farmers' trust in government agricultural agencies in Poland
The purpose of this study was to investigate the levels of farmers' trust toward state agricultural agencies in Poland, to identify its determinants and to develop a model illustrating the relationship between trust and the different dimensions of the ...
Aldona ZAWOJSKA
doaj +1 more source
Freedom of Information: Federal and New York State Laws [PDF]
The initial Freedom of Information Act was created so that the public could have greater access to records possessed by federal government agencies. President Linden B. Johnson signed the Act into law on July 4, 1966 and it went into effect the next year.
Clarke, Janette
core +1 more source
Mathematical model of brain tumour with glia-neuron interactions and chemotherapy treatment [PDF]
Acknowledgements This study was possible by partial financial support from the following Brazilian government agencies: Fundação Araucária, EPSRC-EP/I032606/1 and CNPq, CAPES and Science Without Borders Program Process nos. 17656125, 99999.010583/2013-00
Baptista, Murilo Da Silva +7 more
core +1 more source
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source

