Results 71 to 80 of about 1,634,233 (302)

Synchronised firing patterns in a random network of adaptive exponential integrate-and-fire neuron model [PDF]

open access: yes, 2017
Acknowledgements This study was possible by partial financial support from the following Brazilian government agencies: CNPq, CAPES, and FAPESP (2011/19296-1 and 2015/07311-7).
Baptista, M.S.   +7 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Insourcing Functions Performed by Federal Contractors: Legal Issues [PDF]

open access: yes, 2013
[Excerpt] While agencies are prohibited by federal law and policy from contracting out functions that are “inherently governmental,” other functions could potentially be contracted out.
Manuel, Kate M, Maskell, Jack
core   +2 more sources

TQM-ing OMB: Or Why Regulatory Review Under Executive Order 12,291 Works Poorly and What President Clinton Should Do About It [PDF]

open access: yes, 1994
Reflections are presented on how Pres Clinton should improve the deeply troubled relationship between the OMB and other government agencies.
Eklund, Britta   +2 more
core   +3 more sources

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

open access: yesMolecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Feasibility of the Implementation of Activity-Based Costing (ABC) in Operational Budgeting of Government Agencies (A Case Study of Government Agencies of Isfahan Province) [PDF]

open access: yesحسابداری سلامت, 2012
Introduction: This research investigated the factors affecting implementation of activity based costing (ABC) in operational budgeting of government agencies in Isfahan province.
D. Foroghi   +2 more
doaj  

Determinants of farmers' trust in government agricultural agencies in Poland

open access: yesAgricultural Economics (AGRICECON), 2010
The purpose of this study was to investigate the levels of farmers' trust toward state agricultural agencies in Poland, to identify its determinants and to develop a model illustrating the relationship between trust and the different dimensions of the ...
Aldona ZAWOJSKA
doaj   +1 more source

Freedom of Information: Federal and New York State Laws [PDF]

open access: yes, 2009
The initial Freedom of Information Act was created so that the public could have greater access to records possessed by federal government agencies. President Linden B. Johnson signed the Act into law on July 4, 1966 and it went into effect the next year.
Clarke, Janette
core   +1 more source

Mathematical model of brain tumour with glia-neuron interactions and chemotherapy treatment [PDF]

open access: yes, 2015
Acknowledgements This study was possible by partial financial support from the following Brazilian government agencies: Fundação Araucária, EPSRC-EP/I032606/1 and CNPq, CAPES and Science Without Borders Program Process nos. 17656125, 99999.010583/2013-00
Baptista, Murilo Da Silva   +7 more
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

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