Results 141 to 150 of about 13,350,834 (357)
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Conceptual modeling in insurance agricultural risks
Путеводитель предпринимателя, 2020 The article discusses the possibility of using the method of conceptual modeling for revision of the Concept development of the agricultural insurance, implemented with state support, for the period up to 2020.
V. V. Shcherbakov
doaj
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Assessment of the impact of management commitment and supply chain integration on SMEs' innovation performance: Moderation role of government support. [PDF]
Heliyon, 2023 Chen H +4 more
europepmc +1 more source
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Accelerating NSW: Insights from startups and startup support organisations
Startup support organisations including coworking spaces, accelerators, incubators, and startup hubs (what we call CAISH entities) have increased in recent years but there is limited understanding of their impact on NSW and Australian economies. The NSW
Cetindamar Kozanoglu, Dilek +6 more
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The Unsupportable Support Price: The Government in Paddy Auctions of Northern India [PDF]
In most developing countries, there is an active debate on the changing role of the government in mediating market outcomes. In grain markets in India, this debate assumes a renewed significance, given the excessive accumulation of food stocks in recent ...
J.V. Meenakshi, A. Banerji
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Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
The Child Support Program in Oregon
, 2001 This archived document is maintained by the Oregon State Library as part of the Oregon Documents Depository Program. It is for informational purposes and may not be suitable for legal purposes."Revised February 2001."Title from coverMode of access ...
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<b>If Left Unchecked:</b> Lessons Learned from Unfettered U.S. Government Support of the NIH-Moderna Vaccine. [PDF]
J Law Med Ethics, 2023 Ramachandran R.
europepmc +1 more source