Results 101 to 110 of about 29,049 (260)

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

FEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta, Nidhi Yadav, Subhasmita Das, R. Rajendra Kumar Reddy, Nupur Sharma, Amol Ratnakar Suryawanshi, Jaswinder Singh Maras, Ranjan Kumar Nanda   +7 more
wiley   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Ventajas de incluir la figura de candidato suplente para la elección de gobernador en el Estado de México

Revista del Instituto Electoral del Estado de México. Apuntes Electorales, 2016
En este trabajo se describe la figura jurídica de la suplencia, que en la actualidad está reconocida en la legislación mexicana para diversos cargos de elección federal, estatal y municipal; así, los integrantes del Congreso de la Unión (senadores y
Enrique González de la Paz
doaj  

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

Judicial and police activities of the zemstvo chiefs of the Penza province in the late 19th – early 20th centuries

Известия высших учебных заведений. Поволжский регион: Гуманитарные науки
Background. The article analyzes the activities of zemstvo chiefs in the context of the exercise of judicial, police and administrative powers by these officials in Penza province.
M.N. Shoshkina
doaj   +1 more source

Efficacy of Governor Vessel-Based Acupuncture, Alone or in Combination with Other Therapies, for Acute Lumbar Disc Herniation: A Systematic Review and Meta-Analysis. [PDF]

J Pain Res
Yang S, Guo Q, Zhang M, Zhang W, Ren S.
europepmc   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Women's social care provision in prison has improved but challenges remain: findings from a national survey in England eight years after the 2014 Care Act. [PDF]

BMC Public Health
Buck D, O'Neill A, Marsh N, Stalker K, Plugge E, Hargreaves C, Brimblecombe N, Harriott P, Robinson C, Shaw JJ, Forsyth K.   +10 more
europepmc   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Coccidioidomycosis Masquerading as Malignancy: A Case of Mediastinal Mass and Pericardial Effusion in an Immunocompetent Jamaican Male. [PDF]

Case Rep Infect Dis
Governor SB, Zaidi M, Nepali P, Grigorova Y, Baissari A, Toussaint R, Dabaghyan M, Melendez-Garcia A, Jammal R.   +8 more
europepmc   +1 more source