Results 141 to 150 of about 24,285 (259)
During human immunodeficiency virus (HIV-1) entry, the metastable pretriggered envelope glycoprotein (Env) trimer ((gp120/gp41)3) opens asymmetrically. We present cryo-EM structures of cleaved asymmetric Env trimers in amphipol-lipid nanodiscs.
Yi Qi +9 more
doaj +1 more source
Previous findings have indicated that HIV-1 gp41 like human type I interferon (IFN) could inhibit lymphocyte proliferation and up-modulate MHC class I, II and ICAM-1 molecule expression, and a common epitope exists between gp41 and type I interferon (IFN-
Bai, Yun +6 more
core
Mimicking the pre-hairpin intermediate of gp41
A novel screening platform for potential retroviral fusion inhibitors on the basis of fully functional membrane‐anchored coiled coil lipopeptide receptors has been established. The work comprises the scrutiny of lateral organization of functional lipids in phase separated bilayers and an in‐depth investigation of the biophysical properties of ...
openaire +3 more sources
Distinct allosteric remodeling of HIV-1 Env dynamics on virions by gp41-directed antibodies reveals two modes of neutralization. [PDF]
Xu W +14 more
europepmc +1 more source
Insights into Genome Ejection by a Therapeutic phiKMV-like Bacteriophage. [PDF]
Li J +12 more
europepmc +1 more source

