New advances in the development of a vaccine against paracoccidiodomycosis.
Paracoccidioidomycosis is an endemic Latin American mycosis caused by Paracoccidioides brasiliensis and also by the recently described P. lutzii. The systemic mycosis is the 10th leading cause of death due to infectious diseases in Brazil. As published,
Luiz R R. Travassos +1 more
doaj +1 more source
PREVALENCE of PARACOCCIDIOIDOMYCOSIS INFECTION BY INTRADERMAL REACTION in RURAL AREAS in ALFENAS, MINAS GERAIS, BRAZIL [PDF]
This study aimed to estimate the prevalence of paracoccidioidal infection by intradermal reaction (Delayed-Type Hypersensitivity, DTH) to Paracoccidioides brasiliensis in rural areas in Alfenas, Southern Minas Gerais (MG) State, Brazil, and to assess ...
Camargo, Zoilo Pires de +9 more
core +5 more sources
Artificial Processive Catalytic Systems
A processive catalyst undergoes several rounds of catalysis before it is released from the substrate. The drawing shows possible ways (A–D) in which a synthetic catalyst can interact with the substrate to achieve processivity. Abstract Processive catalysts remain attached to a substrate and perform multiple rounds of catalysis.
Roeland J. M. Nolte +1 more
wiley +1 more source
Paracoccidioidomycosis is a systemic and endemic mycosis, restricted to tropical and subtropical areas of Latin America. The infection is caused by the thermal dimorphic fungus Paracoccidioides brasiliensis and Paracoccidioides lutzii.
Marcela Gaviria +4 more
doaj +1 more source
Evidence for positive selection in putative virulence factors within the Paracoccidioides brasiliensis species complex. [PDF]
Paracoccidioides brasiliensis is a dimorphic fungus that is the causative agent of paracoccidioidomycosis, the most important prevalent systemic mycosis in Latin America. Recently, the existence of three genetically isolated groups in P. brasiliensis was
Daniel R Matute +3 more
doaj +1 more source
Simultaneous infection of human host with genetically distinct isolates of Paracoccidioides brasiliensis [PDF]
This study is the first report on genetic differences between isolates of Paracoccidioides brasiliensis from a single patient. We describe a simultaneous infection with genetically distinct isolates of P.
Arnaud, Adelita Duanra Medeiros do Monte +5 more
core +3 more sources
ABSTRACT gp43 is the main diagnostic antigen for paracoccidioidomycosis (PCM). In vitro, gp43 expression in supernatant fluids of Paracoccidioides brasiliensis cultures can be unstable, and its regulation is poorly understood.
Carvalho, K. C. UNIFESP +3 more
openaire +3 more sources
Immunity and hypersensitivity to gp43 antigen in susceptible and resistant mice infected withParacoccidioides brasiliensis [PDF]
Pathogenic mechanisms underlying paracoccidioidomycosis are still poorly understood. A well-established murine model of resistance (mouse lineage A/Sn) and susceptibility (lineage B10.A) to P. brasiliensis pulmonary infection was here employed to compare immune response to gp43, the major antigenic component of the fungus.
Luiz Claudio, Godoy +2 more
openaire +2 more sources
Semi-nested PCR para a detecção molecular de Paracoccidioides brasiliensis em amostras de tecido [PDF]
INTRODUCTION: Paracoccidioidomycosis is a systemic infection caused by Paracoccidioides brasiliensis. METHODS: In this study, a semi-nested PCR for paracoccidioidomycosis diagnosis was developed. The primers ITS1 and ITS4 were used in the first reaction,
Dionízio Filho, Pedro Sebastião Raimundo +5 more
core +1 more source
Natural history of experimental arthritis induced by Paracoccidioides brasiliensis in wistar rats
INTRODUCTION: Paracoccidioidomycosis (PCM) is the most prevalent systemic mycosis in Latin America. This study aimed to evaluate the natural history of Paracoccidioides brasiliensis-induced experimental arthritis of the knee joints in Wistar rats ...
Eduardo Alexandre Loth +5 more
doaj +1 more source

