Results 251 to 260 of about 142,523 (351)

Safety, tolerability and clinical effects of rovunaptabin, also known as BC007 on fatigue and quality of life in patients with Post-COVID syndrome (reCOVer): a prospective, exploratory, placebo-controlled, double-blind, randomised phase IIa clinical trial (RCT). [PDF]

EClinicalMedicine
Hohberger B, Ganslmayer M, Harrer T, Kruse F, Maas S, Borst T, Heimke-Brinck R, Stog A, Knauer T, Rühl E, Zeisberg V, Skornia A, Bartsch A, Ströbel A, Wytopil M, Merkel C, Hofmann S, Schmidt KG, Lakatos P, Schottenhamml J, Herrmann M, Mardin C, Rech J.   +22 more
europepmc   +1 more source

Evaluation of Cellular Dielectric Spectroscopy, a Whole-Cell, Label-Free Technology for Drug Discovery on Gi-Coupled GPCRs

, 2007
Matthew F. Peters, Katharine S. Knappenberger, Deidre Wilkins, Linda A. Sygowski, Lois Ann Lazor, Jianwei Liu, Clay W. Scott   +6 more
openalex   +1 more source

GPCR desensitization: Acute and prolonged phases.

Cellular Signalling, 2018
S. Rajagopal, S. Shenoy
semanticscholar   +1 more source

Pharmacogenetics of follicle‐stimulating hormone action in the male

Andrology, EarlyView.
Abstract Male factor infertility (MFI) is involved in half of the cases of couple infertility. The follicle‐stimulating hormone (FSH) therapy is considered efficient to improve semen parameters and pregnancy rate in patients with idiopathic MFI, following the lesson learned from hypogonadotropic hypogonadism.
Andrea Graziani, Giuseppe Grande, Raffele Scafa, Riccardo Selice, Andrea Garolla, Maria Santa Rocca, Cinzia Vinanzi, Alberto Ferlin   +7 more
wiley   +1 more source

Rewiring β₂-adrenergic receptor signaling: harnessing non-canonical GRK functions to treat metabolic diseases. [PDF]

Signal Transduct Target Ther
Cullum SA, Bock A.
europepmc   +1 more source

Comparison on Functional Assays for Gq-Coupled GPCRs by Measuring Inositol Monophospate-1 and Intracellular Calcium in 1536-Well Plate Format [PDF]

, 2008
Ke Liu, Steve Titus, Noel Southall, Pingjun Zhu, James Inglese, Christopher P. Austin, Wei Zheng   +6 more
openalex   +1 more source

Distinct conformations of GPCR–β-arrestin complexes mediate desensitization, signaling, and endocytosis

Proceedings of the National Academy of Sciences of the United States of America, 2017
T. Cahill, A. Thomsen, Jeffrey Tarrasch, Bianca Plouffe, Anthony H. Nguyen, Fan Yang, Li-Yin Huang, Alem W. Kahsai, D. Bassoni, Bryant J. Gavino, J. Lamerdin, Sarah Triest, A. Shukla, B. Berger, John Little, Albert Antar, Adi Blanc, C. Qu, Xin Chen, Kouki Kawakami, A. Inoue, J. Aoki, J. Steyaert, Jin-peng Sun, M. Bouvier, G. Skiniotis, R. Lefkowitz   +26 more
semanticscholar   +1 more source

The Oxytocin Receptor in Spermatozoa May Originate From Both Spermatogenesis and Epididymal Maturation, and Regulates Capacitation

Andrology, EarlyView.
Abstract Background The oxytocin receptor (OR) is a G‐protein‐coupled receptor recently identified in human spermatozoa, whose origin and role in sperm physiology remain unknown. Objectives In this study, using the pig as a model, we examine the presence of the OR in ejaculated spermatozoa through immunofluorescence and immunoblotting, and investigate ...
Jesús Martínez‐Hernández, Ferran Garriga, Adeel Ahmad, Lorena Padilla, Carolina Maside, Sergi Bonet, Isabel Barranco, Jordi Roca, Luis Miguel Pastor, Marc Yeste   +9 more
wiley   +1 more source

Chemical biology approaches to resolve the subcellular GPCR signaling landscape. [PDF]

Nat Chem Biol
Bock A, Lobingier BT, Stoeber M, Tsvetanova NG.   +3 more
europepmc   +1 more source

Double GPCR trouble [PDF]

, 2008
Charlotte Harrison
openalex   +1 more source