Results 331 to 340 of about 142,523 (351)
Trends in GPCR drug discovery: new agents, targets and indications
Nature Reviews Drug Discovery, 2017 Alexander S Hauser +2 more
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TRUPATH, an open-source biosensor platform for interrogating the GPCR transducerome
Nature Chemical Biology, 2020 G-protein-coupled receptors (GPCRs) remain major drug targets, despite our incomplete understanding of how they signal through 16 non-visual G-protein signal transducers (collectively named the transducerome) to exert their actions.
Jeffrey F Diberto +2 more
exaly +2 more sources
GPCR Dynamics: Structures in Motion
Chemical Reviews, 2017 Naomi R Latorraca, A J Venkatakrishnan
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Combinatorial expression of GPCR isoforms affects signalling and drug responses
Nature, 2020 Maria Marti-Solano +2 more
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Recent Progress in Assays for GPCR Drug Discovery.
American Journal of Physiology - Cell Physiology, 2022G-protein coupled receptors (GPCRs), also known as 7 transmembrane receptors, are the largest family of cell surface receptors in eukaryotes. There are ~800 GPCRs in human, regulating diverse physiological processes.
Shimeng Guo +3 more
semanticscholar +1 more source
An online resource for GPCR structure determination and analysis
Nature Methods, 2019 Christian Munk +2 more
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GPCRdb in 2021: integrating GPCR sequence, structure and function
Nucleic Acids Research, 2021Albert Jelke Kooistra +2 more
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Single-molecule FRET imaging of GPCR dimers in living cells
Nature Methods, 2021Wesley B Asher +2 more
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GPCR drug discovery: new agents, targets and indications.
Nature reviews. Drug discoveryJavier Sánchez Lorente +5 more
semanticscholar +1 more source