Results 191 to 200 of about 67,843 (252)

Improving AlphaFold2 Performance in Virtual Screens Targeting GPCRs by Enhancing Binding-Site Conformational Sampling. [PDF]

J Chem Inf Model
Mitjavila-Domènech N, Díaz-Holguín A, Hu H, Kahlous NA, Cabeza de Vaca I, Wallner B, Carlsson J.   +6 more
europepmc   +1 more source

Synergistic Effects of Thyroxine and Nano‐Melatonin on Post‐Thaw Sperm Quality, Antioxidant Defence and Fertility of Cryopreserved Simmental Bull Semen

Veterinary Medicine and Science, Volume 12, Issue 6, November 2026.
Effects of thyroxine (T) and nano‐melatonin (NM) supplementation on cryopreserved Simmental bull semen were evaluated. The combination of thyroxine (0.5 µg/dL) and nano‐melatonin (30 µg/dL) significantly improved post‐thaw sperm motility, membrane integrity, antioxidant status, and fertility while reducing oxidative stress and apoptosis. These findings
Marwa Abonagy, Ahmed Arisha, Maha Salama, Mohey Ashour, Mustafa Shukry, Sameh Shedeed, Ahmed Shehabeldin, Nagi El‐Shafai, Zein Ibrahim, Shawky Mahmoud, Michel Saad, Ahmed Alameen, Rasha Yassin Elkhidr, Osama Hassan Alif, Arafat Khalphallah, Enas Elmeligy, Khaled Abdulaziz Khesruf, Enas Ahmed Abdelhafez, Alaa Algabary   +18 more
wiley   +1 more source

Recent Advances in GPCR Ligand Discovery Using DNA-Encoded Library Technology: From Affinity Binding to Functional Bias and Allosteric Modulation. [PDF]

ACS Med Chem Lett
Zhou R, Wang J, Li X, An Y.
europepmc   +1 more source

The GPCR Connection: Linking Alzheimer's Disease and Glioblastoma. [PDF]

J Cell Mol Med
Caniceiro AB, Agostinho SP, Piochi LF, Rosário-Ferreira N, Moreira IS.   +4 more
europepmc   +1 more source

Mechanistic and therapeutic insights into class A GPCR dimers in neuropsychiatric disorders. [PDF]

NPJ Drug Discov
Wang Z, Wang L, Zhang S.
europepmc   +1 more source

Design of a metabolically-stable peptide therapeutic with triple-hormone-receptor agonist activity. [PDF]

J Comput Aided Mol Des
Vishnoi S, Hudson S, Bhattacharya S, Thompson D.   +3 more
europepmc   +1 more source

GPCRs as key regulators in wound healing. [PDF]

Front Cell Dev Biol
Chen H, Zheng K, Xiao Y, Feng X, Zhang C, Zhang T, Luo F, Chuan H, Zheng H, Deng C, Li W.   +10 more
europepmc   +1 more source

Assessment of generative de novo peptide design methods for G protein-coupled receptors. [PDF]

PLoS One
Junker H, Schoeder CT.
europepmc   +1 more source