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GPR54 is a target for suppression of metastasis in endometrial cancer
GPR54 is a target for suppression of metastasis in endometrial canceropenaire +1 more source
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The KiSS1/GPR54 system in fish
Peptides, 2009The KiSS1/GPR54 system has now been identified in non-mammalian vertebrates. Transcripts encoding for KiSS1 and its receptor, GPR54, have been isolated from a number of fish species. The expression of their genes was characterized in the context of temporal and spatial expression and in response to endocrine manipulations.
Abigaïl Elizur
exaly +4 more sources
Roles of the kisspeptin/GPR54 system in pathomechanisms of atherosclerosis
Nutrition, Metabolism and Cardiovascular Diseases, 2020Kisspeptin-10 (KP-10), a potent vasoconstrictor and inhibitor of angiogenesis, and its receptor, GPR54, have currently received much attention with respect to atherosclerosis, since both KP-10 and GPR54 are expressed at high levels in atheromatous plaques and restenotic lesions after wire-injury.
Kengo Sato, Takuya Watanabe
exaly +3 more sources
Reviews in Endocrine and Metabolic Disorders, 2007
Idiopathic hypogonadotropic hypogonadism (IHH) is a condition characterized by absence of sexual maturation in the setting of low sex steroids and low/normal gonadotropins. Despite its rarity, considerable genetic heterogeneity and phenotypic variability exists in this disorder.
Stephanie Seminara +1 more
exaly +3 more sources
Idiopathic hypogonadotropic hypogonadism (IHH) is a condition characterized by absence of sexual maturation in the setting of low sex steroids and low/normal gonadotropins. Despite its rarity, considerable genetic heterogeneity and phenotypic variability exists in this disorder.
Stephanie Seminara +1 more
exaly +3 more sources
Ligand selectivity of the sea bass kisspeptin receptors gpr54-1b and gpr54-2b
, 2013 The Kiss/Gpr54 system is considered to be an essential regulator of the reproductive axis in most vertebrate species. The existence of paralogous kisspeptin genes as well as kisspeptin receptor genes has quite recently been reported in several fish and amphibian species.
Espigares, F. +3 more
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Female reproductive maturation in the absence of kisspeptin/GPR54 signaling
Nature Neuroscience, 2011 Puberty onset is initiated in the brain by activation of gonadotropin-releasing hormone (GnRH) neurosecretion. Different permissive signals must be integrated for the initiation of reproductive maturation; however, the neural circuits controlling timely awakening of the reproductive axis are not understood.
Mayer, C., Boehm, U.
openaire +4 more sources