Results 181 to 190 of about 4,181 (199)

Expression of a GPR54-like but no agonistic effect of mammalian kisspeptins in trout

2007
Kisspeptins and their G protein-coupled receptor, play a fundamental role in the control of reproductive function in mammals. Here we show that the anterior brain and testis of the trout express a GPR54-like transcript. Trout at 3 stages of maturation were submitted to in vivo treatment with large amounts or repeated injections of mouse or human C ...
Goupil, Anne-Sophie, Lareyre, Jean-Jacques, Le Bail, Pierre-Yves, Kah, Olivier, Caraty, Alain, Le Gac, Florence   +5 more
openaire   +3 more sources

[KISS-1/GPR54 genes and their role in reproduction].

Yi chuan = Hereditas, 2009
KISS-1 gene and its receptor gene GPR54 play key roles in the initiation of puberty onset. The peptide product of the KiSS-1 gene, Kisspeptins stimulate gonadotrophins release to initiate puberty through the expression of GPR54 gene in the brain. So the level of KISS-1 and GPR54 mRNA in hypothalamus was very high on the onset of puberty. The expression
Tao, Feng, Ming-Xing, Chu, Ying-Jie, Zhang   +2 more
openaire   +1 more source

The KiSS-1 receptor GPR54 is essential for the development of the murine reproductive system

Biochemical and Biophysical Research Communications, 2003
Galya Vassileva, Joseph A Hedrick, Frederick J Monsma   +2 more
exaly  

KiSS1 and its G-protein-coupled receptor GPR54 in cancer development and metastasis

Cancer and Metastasis Reviews, 2012
Dali Li, Sung-Gook Cho, Stefan Siwko
exaly  

GPR54 and KiSS-1: Role in the regulation of puberty and reproduction

Reviews in Endocrine and Metabolic Disorders, 2007
Ursula Kaiser, Wendy Kuohung, Kaiser Ursula B   +2 more
exaly  

Faculty Opinions recommendation of Kisspeptin/Gpr54-independent gonadotrophin-releasing hormone activity in Kiss1 and Gpr54 mutant mice.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature, 2009
Pamela Mellon, Alexander Kauffman
openaire   +1 more source

Synthesis and structure–activity relationships of 2-acylamino-4,6-diphenylpyridine derivatives as novel antagonists of GPR54

Bioorganic and Medicinal Chemistry, 2010
Tetsuya Ohtaki, Yoshihiro Takatsu
exaly  

A High-Throughput Small-Molecule Ligand Screen Targeted to Agonists and Antagonists of the G-Protein-Coupled Receptor GPR54

SLAS Discovery, 2010
Ursula Kaiser, Wendy Kuohung, Marcie A Glicksman   +2 more
exaly  

Design and synthesis of downsized metastin (45–54) analogs with maintenance of high GPR54 agonistic activity

Bioorganic and Medicinal Chemistry Letters, 2006
Nobutaka Fujii, Shinya Oishi, Ayumu Niida   +2 more
exaly  

Structure–activity relationship study on small peptidic GPR54 agonists

Bioorganic and Medicinal Chemistry, 2006
Nobutaka Fujii, Shinya Oishi, Hiroaki Ohno   +2 more
exaly