Results 101 to 110 of about 1,817 (168)

Retraction: The Succinate Receptor GPR91 Is Involved in Pressure Overload-Induced Ventricular Hypertrophy. [PDF]

PLoS One
PLOS One Editors.
europepmc   +1 more source

SDHA Deficiency in Hepatocellular Carcinoma Promotes Tumor Progression through Succinate-Induced M2 Macrophage Polarization. [PDF]

Oncol Res
Li X, Ma L, Shen C, Gu R, Dong S, Liu M, Xiao Y, Liu W, Liu Y, Zhao C.   +9 more
europepmc   +1 more source

Evaluating the link between the GPR91 receptor and renin in the pathogenesis of diabetic retinopathy

Diabetic retinopathy is the leading cause of blindness in people of working age. A hormonal system called renin-angiotensin is implicated in the development of diabetic retinopathy, and new evidence indicates that its blockade improves aspects of the ...

core  

Structural analysis reveals that water molecules mediate self-activation of GPR99. [PDF]

Commun Biol
Xiao M, Bao X, Guo Y, Li J, Chang T, Zhong F, Mao X, Li M, Liu S, Chen W, Zhao L, Wang C, Liu H.   +12 more
europepmc   +1 more source

Deficiency in the Metabolite-Sensing Receptor SUCNR1 (GPR91) Leads to Outer Retinal Lesions akin to dry-Age-Related Macular Degeneration

, 2013
Age-related macular degeneration (AMD) is a prominent cause of blindness in the Western world. To date, its molecular pathogenesis as well as the sequence of events leading to retinal degeneration remain largely ill-defined.
Favret, Sandra, Carballido, Jose, Sapieha, Przemyslaw, Rubic-Schneider, Tina   +3 more
core  

Immunometabolic regulation of cardiac macrophages in heart failure with preserved ejection fraction. [PDF]

Front Immunol
Liang J, Su M, Liu R, Li T, Qin Z, Wang Y.   +5 more
europepmc   +1 more source

From gut microbiota metabolism to microvascular injury: Exploring the role and mechanisms of gut microbiota in obesity-induced coronary microcirculation dysfunction. [PDF]

Virulence
Liu Y, Wang Y, Teng H, Nie W, Qiao X, Shen Y, Wang Z, Yao X.   +7 more
europepmc   +1 more source

Molecular insights into ligand recognition and signaling of OXGR1. [PDF]

Nat Commun
Liu A, Liu Y, Long Y, Ye RD.
europepmc   +1 more source

Gemigliptin Alleviates Succinate Induced Endoplasmic Reticulum Stress and Activation of Hepatic Stellate Cells. [PDF]

J Korean Med Sci
Do DV, Nguyen G, Park SY, Cho EH.
europepmc   +1 more source

Succinate-mediated metabolic alterations and signaling in RA: mechanisms and therapeutic implications. [PDF]

Front Immunol
Fan Y, Wang N, Zhao C, Zhang Z.
europepmc   +1 more source