ABSTRACT The etiopathogenesis of Autism Spectrum Disorder (ASD) encompasses complex interactions between genetic and environmental risk factors. The high prevalence of gastrointestinal disorders in autistic individuals has propelled a growing interest in the possible involvement of gut dysbiosis in ASD pathogenesis.
Laura Sandoni +6 more
wiley +1 more source
Prolonged exposure to ultraviolet B (UVB) radiation causes persistent skin inflammation, resulting in oxidative stress, collagen breakdown, and progressive loss of collagen.
Meri +3 more
doaj +1 more source
Molecular characterization of two glutathione peroxidase genes in Mytilus galloprovincialis and their transcriptional responses to sub-chronic arsenate and cadmium exposure [PDF]
Glutathione peroxidases (GPxs) are key enzymes in the antioxidant defense system of living organisms, and protect organisms against oxidative stresses.
Q Wang +6 more
doaj +1 more source
Atomically precise metal cluster enzymes for pathological tissue regeneration
Schematic illustration of atomically precise metal cluster enzymes (MCEs) for pathological tissue regeneration. Atomically precise MCEs can modulate biological processes, such as attenuation of inflammatory responses, eradication of bacterial pathogens, regulation of angiogenesis, and promotion of cell development.
Ziqiang Xiong +11 more
wiley +1 more source
Investigation of the Anti-Oxidative Stress Effects of Organic Acid and Silver Nanoparticles Coated on Zeolite in the Liver and Intestine of Broiler Chickens [PDF]
Extended Abstract Background: Oxidative stress is one of the major growth-limiting factors that occurs due to the excessive production of reactive oxygen species (ROS) and can lead to tissue damage in vital organs such as the liver and intestine.
Fatemeh Asgharnezhad +3 more
doaj
Harnessing ferroptosis from multilayer defense networks to nanoplatforms for specific cancer therapy
Nanomaterials target metabolically‐regulated ferroptosis for cancer therapy. Iron‐based or alternative nanoplatforms integrate ferroptosis with chemotherapy, immunotherapy, or radiotherapy. They enable stimulus‐responsive therapies (photothermal, photodynamic, sonodynamic) activated by near‐infrared, light, or ultrasound, achieving potent synergistic ...
Xinyue Xu +5 more
wiley +1 more source
High atmospheric pressure (120 kPa) in deep underground counteracts humidity‐induced physiological stress in plants, stabilizing water balance and enhancing antioxidative defenses. This synergy boosts biomass despite elevated humidity, demonstrating sustainable deep underground agriculture potential under climate uncertainty.
Yuxin He +6 more
wiley +1 more source
Time course of oxidative damage in different brain regions following transient cerebral ischemia in gerbils [PDF]
The time course of oxidative damage in different brain regions was investigated in the gerbil model of transient cerebral ischemia. Animals were subjected to both common carotid arteries occlusion for 5 min.
Al-Dalain, Saied M. +4 more
core
Monoterpenoid selenophenes derived from (−)-carvone with GPx-like activity
Mentoselenophenone 1 was prepared by a one-step reaction of the natural product (−)-carvone with SeBr2. Several derivatives of 1 were also prepared. All but lactam 8 showed GPx-like activity, increasing in the order 3 < 1 < 7 < 2 < 6.
João P. Telo +5 more
openaire +2 more sources
Role of selenium in the pathophysiology of cardiorenal anaemia syndrome
Abstract Chronic kidney disease (CKD) and cardiovascular disease (CVD) have multiple bidirectional mechanisms, and anaemia is one of the critical factors that are associated with the progression of the two disorders [referred to as cardiorenal anaemia syndrome (CRAS)].
Shigeyuki Arai +2 more
wiley +1 more source

