Results 131 to 140 of about 48,780 (260)

Combating ageing beyond the cell: Emerging roles of extracellular proteostasis

The FEBS Journal, EarlyView.
Ageing challenges the body's ability to maintain a stable and functional proteome, leading to protein damage and aggregation both inside and outside cells. This review focuses on the less well understood mechanisms of extracellular protein quality control and how they become disrupted in ageing, particularly in neurodegenerative diseases.
Siddharth R. Venkatesh, Ivan Gallotta, Bolanle F. Olabiyi, Yoon Hee Choi, Sarah Inglesfield, Janet R. Kumita, Collin Y. Ewald, Della C. David   +7 more
wiley   +1 more source

Differential Modulation by Polystyrene Microplastics on the Toxic Effects of Pyrene and Its Derivatives in the Blue Mussel <i>Mytilus edulis</i>: Insights from Hemolymph Biomarkers. [PDF]

Toxics
Zhu R, Li S, Lu Y, Chen W, Xie M, Xu K, Zhou X.   +6 more
europepmc   +1 more source

Malaria mosquito antimicrobial defence requires immunity and detoxification gene regulation by Lola

Insect Molecular Biology, EarlyView.
Malaria mosquito antimicrobial defence requires upregulation of lola. Attenuation of lola in the midgut of Anopheles albimanus mosquitoes inhibits the upregulation of immunity genes induced by challenge. Putative target genes of the Lola transcription factor were revealed by lola attenuation, including Cecropin‐C, Draper, PPAF2, Clip‐domain serine ...
Heidi Espadas‐Álvarez, Verónica Valverde‐Garduño   +1 more
wiley   +1 more source

Redox Imbalance and Antioxidant Adaptation in Acute Ischemic Stroke: Temporal Changes in Enzymatic and Non-Enzymatic Markers. [PDF]

Molecules
Garbarek J, Markiel JK, Rzepka W, Glazik K, Pitek M, Szewczyk-Golec K, Kukulska-Pawluczuk B, Soja-Kukieła N, Woźniak A, Nuszkiewicz J.   +9 more
europepmc   +1 more source

Haematological and histopathological monitoring of monosodium glutamate–supplemented feeding in rainbow trout (Oncorhynchus mykiss): A possible modelling for a single health approach

Journal of Fish Biology, EarlyView.
Abstract The aim of this study was to investigate the potential effects of monosodium glutamate (MSG), a known flavour enhancer added to many ready‐to‐eat foods, as a feed additive in rainbow trout (Oncorhynchus mykiss). Evaluating the effects of MSG on aquatic organisms will fill the knowledge gap in this field by monitoring the haematological indices
Gonca Alak, Furkan Bedir, Aslı Çilingir Yeltekin, Serkan Yıldırım, Eylül Ecrin Ekiz, Nisa Gül Yiğit, Esat Mahmut Kocaman, Metin Kiliçlioğlu, Tuba Akbey, Elif Zeynep Özçelik, Koray Koşar, Muhammet Alaeddin Ekiz, Arzu Ucar, Ahmet Atmaca, Melihat Pilgi, Veysel Parlak, Muhammed Atamanalp   +16 more
wiley   +1 more source

The effects of agmatine treatment on cisplatin-induced hepatotoxicity: an experimental rat study. [PDF]

Sao Paulo Med J
Yeniceri M, Senoymak MC, Bas S, Salmanoglu M, Tanoglu A.   +4 more
europepmc   +1 more source

High‐throughput multispecies quantitative polymerase chain reaction assays to study the effects of acute thermal stress in three species of Acipenser sturgeon

Journal of Fish Biology, EarlyView.
Abstract Fishes experience thermal stress in their natural environment that can be caused by natural or anthropogenic factors and can directly affect their physiology. In this study, we developed a multispecies OpenArray™ qPCR (quantitative polymerase chain reaction) ‘chip’ to measure the effects of acute thermal stress on the mRNA response of ...
Hossein Haghighi, Kyle Madden, William S. Bugg, Faith M. Penny, Scott A. Pavey, Nicholas J. Bernier, Kenneth M. Jeffries   +6 more
wiley   +1 more source

Evaluation of agmatine efficacy in contrast-induced nephropathy: experimental evidence in rat model. [PDF]

Acta Cir Bras
Yeniçeri M, Baş S, Şenoymak MC, Salmanoğlu M, Tanoğlu A.   +4 more
europepmc   +1 more source

Integrated multitissue analysis reveals distinct oxidative stress responses during recovery from cold shock in the Amazonian fish Colossoma macropomum

Journal of Fish Biology, EarlyView.
Abstract Tambaqui (Colossoma macropomum) is a tropical fish widely cultivated in South America. The increasing demand for this species has heightened interest in its cultivation in subtropical regions with greater thermal variability, where cold shock may induce oxidative stress. This study evaluated the effects of cold shock and subsequent recovery on
Naiara Melo, Isaac Konig, Stefania Priscilla de Souza, Maria Fernanda Aquino Freitas, Daniella Aparecida de Jesus Paula, Ronald Kennedy Luz, Priscila Vieira Rosa, Luis David Solis Murgas   +7 more
wiley   +1 more source

Evaluation of oxidative stress in ill neonatal foals: a preliminary study. [PDF]

J Vet Intern Med
Bindi F, Cingottini D, de Marchi L, Sala G, Vitale V, Sgorbini M.   +5 more
europepmc   +1 more source