Ischemia–Reperfusion Injury: Molecular Mechanisms and Therapeutic Interventions
Multiorgan ischemia–reperfusion injury begins with ischemia‐induced ATP depletion and ionic imbalance, followed by reperfusion‐triggered mitochondrial ROS/RNS bursts, regulated cell death, and DAMP release. Sterile inflammation converges on endothelial–immune–coagulation crosstalk, where NETs drive immunothrombosis, no‐reflow, and remote organ injury ...
Peng An +4 more
wiley +1 more source
Preventive Effect of Gallic Acid-Loaded Carrageenan Nanoparticles Against Cerebral Ischemia/Reperfusion Injury in Rat: Modulation of Oxidative Pathway. [PDF]
Hajizadeh Moghaddam A +5 more
europepmc +1 more source
Redox signals and oxidative stress in the control of mitochondrial protein import
Abstract Mitochondrial protein import is essential for organelle biogenesis and cellular homeostasis. It operates in an environment that is intrinsically shaped by redox chemistry. Mitochondria are major sources of reactive oxygen species (ROS), which arise as by‐products of oxidative phosphorylation. Cells therefore maintain sophisticated ROS‐handling
Lidwina Hasberg +3 more
wiley +1 more source
3',4'-Dihydroxyflavonol has a positive effect on the cerebellum oxidant/antioxidant system and BDNF and transmitter levels in focal brain ischemia-reperfusion. [PDF]
Coskun N +6 more
europepmc +1 more source
Dietary norbixin (0.15 g/kg) optimally promotes growth, immunocompetence, antioxidant defence, gut microbial balance, carotenoid accumulation, and overall nutritional quality in Macrobrachium nipponense. ABSTRACT Background Natural carotenoids have gained considerable attention in aquaculture due to their potential to enhance growth performance ...
Mohammad Ettefaghdoost +2 more
wiley +1 more source
Oxidative stress and antioxidant markers in oral leukoplakia: a systematic review and meta-analysis. [PDF]
Chen X, Shao M, Liu L, Xie H, Guo J.
europepmc +1 more source
Co‐exposure to arsenic and cadmium alters metal accumulation and oxidative stress in goldfish. Selenium reduces arsenic bioaccumulation and lipid peroxidation while enhancing antioxidant defences. Findings highlight metal‐specific interactions, with selenium offering partial protection, emphasizing ecological risks and the importance of monitoring ...
Sarina Hosseinkhani +2 more
wiley +1 more source
The SQSTM1/<i>p62</i> of Pacific White Shrimp (<i>Litopenaeus vannamei</i>) Is Involved in the Oxidative Stress Induced by Ammonia Exposure. [PDF]
Lu W +5 more
europepmc +1 more source
Crataegus oxyacantha extract at 0.4 mL/L improved cardiac function in broilers under cold stress and high altitude by increasing nitric oxide synthase gene expression, boosting nitric oxide, reducing endothelin‐1 gene expression, and lowering oxidative‐inflammatory stress, offering a natural solution to mitigate pulmonary hypertension syndrome ...
Behnam Ahmadipour +3 more
wiley +1 more source
Form-specific selenium supplementation in poultry: linking bioefficacy to mechanisms and precision applications. [PDF]
Zhou J +9 more
europepmc +1 more source

