Results 231 to 240 of about 48,780 (260)

Gpx 4 is involved in the proliferation, migration and apoptosis of glioma cells

Pathology - Research and Practice, 2017
Glioma is one of the most common and aggressive types of human brain tumor, it is important to explore novel glioma-associated genes. In this report, we defined Gpx4 as a therapeutic target for glioma. Western blot and immunohistochemistry(IHC) analysis revealed that the protein level of Gpx4 was higher in glioma tissues and cell lines.
Hongyu, Zhao, Bin, Ji, Jianguo, Chen, Qingfeng, Huang, Xueguan, Lu   +4 more
openaire   +2 more sources

Genetic variations of gpx-4 and male infertility in humans.

Biology of reproduction, 2003
Phospholipid hydroperoxide glutathione peroxidase (PHGPx), the product of gpx-4, is the major selenoprotein in sperm and is considered essential for fertilization because of its multiple roles in spermatogenesis, such as hydroperoxide detoxification, formation of the mitochondrial capsule, and chromatin condensation.
MAIORINO, MATILDE, BOSELLO TRAVAIN, VALENTINA, URSINI, FULVIO, FORESTA, CARLO, GAROLLA, ANDREA, M. SCAPIN, H. SZTAJER, L. FLOHE   +7 more
openaire   +2 more sources

Gutta percha removal utilizing GPX instrumentation.

Journal (Canadian Dental Association), 1992
Two studies were performed in order to test the efficiency of GPX rotary instrumentation in removing gutta percha from endodontically-treated extracted teeth. A pilot project compared GPX to gates glidden instrumentation, and then a GPX technique was performed on 60 obturated mesial canals of mandibular molars.
P E, Teplitsky, D, Rayner, I, Chin, R, Markowsky   +3 more
openaire   +1 more source

GPx-1-encoded adenoviral vector attenuates dopaminergic impairments induced by methamphetamine in GPx-1 knockout mice through modulation of NF-κB transcription factor

Food and Chemical Toxicology, 2021
Ji Hoon Jeong, Seung-Yeol Nah, Xin Gen Lei   +2 more
exaly  

Insight from GPxs structure and function

2007
The multigene family of GPxs encodes for tetrameric and monomeric enzymes both containing either a selenocysteine (Sec) or cysteine (Cys) residue at the catalytic site. Monomeric GPxs carry deletions of the subunit interfaces. The Sec containing homologues are found in vertebrates, and, with a scattered presence, in lower organisms.
openaire   +1 more source

An adenoviral vector encoded with the GPx-1 gene attenuates memory impairments induced by β-amyloid (1-42) in GPx-1 KO mice via activation of M1 mAChR-mediated signalling

Free Radical Research, 2021
Ji Hoon Jeong, Seung-Yeol Nah, Yoon Hee Chung   +2 more
exaly  

Possible mechanistic paths of the enzymatic activity of GPx

2011
Glutathione peroxidases (GPx, Fig. 1) belong to a widespread family of proteins that, over the years, have been discovered in almost all kingdoms of life.[1] They catalyze the reduction of H2O2 or organic hydroperoxides to water or corresponding alcohols, thus mitigating their toxicity.[2] The global reaction is ROOH+2GSH  GSSG+ROH+H2O, where GSH ...
ORIAN, LAURA, TOPPO, STEFANO, MAIORINO, MATILDE, URSINI, FULVIO, POLIMENO, ANTONINO   +4 more
openaire   +1 more source

GPX

2004
Daxin Jiang, Jian Pei, Aidong Zhang
openaire   +1 more source

The influence of calf selenium status on GPx-1 and 3 activity and liver GPx-1 mRNA

2022
openaire   +1 more source

Mountain-cultivated ginseng protects against cognitive impairments in aged GPx-1 knockout mice via activation of Nrf2/ChAT/ERK signaling pathway

Journal of Ginseng Research, 2023
Yi Lee, Naveen Sharma, Bao Trong Nguyen   +2 more
exaly