Results 111 to 120 of about 90,989 (277)

On Graded Rings, II ($\mathbf{Z}^n$-graded rings)

open access: yesTokyo Journal of Mathematics, 1978
GOTO, Shiro, WATANABE, Keiichi
openaire   +3 more sources

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

Graded gamma rings

open access: yes, 2014
We introduce graded gamma rings from a more general point of view via methods developed by Krasner and Halberstadt for graded rings. We propose three equivalent aspects of studying graded gamma rings, nonhomogeneous, semihomogeneous and homogeneous.
openaire   +2 more sources

Tumor mutational burden as a determinant of metastatic dissemination patterns

open access: yesMolecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal   +4 more
wiley   +1 more source

Nonlinear Analysis on Buckling and Postbuckling of Stiffened FGM Imperfect Cylindrical Shells Filled Inside by Elastic Foundations in Thermal Environment Using TSDT

open access: yesLatin American Journal of Solids and Structures
The main aim of this paper is to investigate analytically nonlinear buckling and post-buckling of functionally graded stiffened circular cylindrical shells filled inside by Pasternak two-parameter elastic foundations in thermal environments and under ...
Pham Minh Vuong, Dao Van Dung
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Dynamic Analysis of Imperfect FGM Circular Cylindrical Shells Reinforced by FGM Stiffener System Using Third Order Shear Deformation Theory in Term of Displacement Components

open access: yesLatin American Journal of Solids and Structures
This paper presents dynamic analysis of an eccentrically stiffened imperfect circular cylindrical shells made of functionally graded materials (FGM), subjected to axial compressive load and filled inside by elastic foundations in thermal environments by ...
Nguyen Dinh Duc, Hoang Thi Thiem
doaj   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

open access: yesMolecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta   +10 more
wiley   +1 more source

Research on Free Vibration Frequency Characteristics of Rotating Functionally Graded Material Truncated Conical Shells with Eccentric Functionally Graded Material Stringer and Ring Stiffeners

open access: yesLatin American Journal of Solids and Structures
In this research work, an exact analytical solution for frequency characteristics of the free vibration of rotating functionally graded material (FGM) truncated conical shells reinforced by eccentric FGM stringers and rings has been investigated by the ...
Dao Van Dung, Hoang Thi Thiem
doaj   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

open access: yesMolecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

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