Results 81 to 90 of about 90,989 (277)
Journal of Pure and Applied Algebra, 2012 Let $ $ be a cancelation monoid with the neutral element $e$. Consider a $ $-graded ring $A=\oplus_{ \in }A_ $, which is not necessarily commutative. It is proved that $A_e$, the degree-$e$ part of $A$, is a local ring in the classical sense if and only if the graded two-sided ideal $\mathfrak{M}$ of $A$ generated by all non-invertible homogeneous
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Molecular Oncology, EarlyView.A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira +14 more
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$PBW$-deformations of graded rings
, 2017 We prove in a very general framework several versions of the classical Poincar\'e-Birkhoff-Witt Theorem, which extend results from [BeGi, BrGa, CS, HvOZ, WW].
Ardizzoni, Alessandro +2 more
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Molecular Oncology, EarlyView.This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian +10 more
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Molecular Oncology, EarlyView.A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath +13 more
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A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
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Homotopy theory of modules over diagrams of rings
Proceedings of the American Mathematical Society, Series B, 2014 Given a diagram of rings, one may consider the category of modules over them. We are interested in the homotopy theory of categories of this type: given a suitable diagram of model categories ℳ(𝓈) (as 𝓈 runs through the diagram ...
J. P. C. Greenlees, B. Shipley
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Molecular Oncology, EarlyView.This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad +17 more
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Generalized rees rings and arithmetical graded rings
Journal of Algebra, 1983 0. INTRODUCTION In this paper we study graded rings with an arithmetical ideal theory for the graded ideals, e.g., Gr-Dedekind and Gr-principal ideal rings. If these rings are positively graded rings, then the structure of Gr-Dedekind and of Gr-principal ideal rings is easily investigated and it is much like the structure of the ungraded equivalents ...
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Molecular Oncology, EarlyView.Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard +12 more
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