Results 61 to 70 of about 172,487 (303)
Microbial exopolysaccharide production by polyextremophiles in the adaptation to multiple extremes
FEBS Letters, EarlyView.Polyextremophiles are microorganisms that endure multiple extreme conditions by various adaptation strategies that also include the production of exopolysaccharides (EPSs). This review provides an integrated perspective on EPS biosynthesis, function, and regulation in these organisms, emphasizing their critical role in survival and highlighting their ...
Tracey M Gloster, Ebru Toksoy Öner
wiley +1 more source
On elliptic problems with a nonlinearity depending on the gradient
Opuscula Mathematica, 2009 We investigate the solvability of the Neumann problem \((1.1)\) involving the nonlinearity depending on the gradient. We prove the existence of a solution when the right hand side \(f\) of the equation belongs to \(L^m(\Omega )\) with \(1 \leq m \lt 2\).
openaire +2 more sources
Enhanced Approach to Consistency in Gradient-Dependent Plasticity [PDF]
Advances in Structural Engineering, 2004 This note proposes a modification of gradient-dependent plasticity to improve convergence. In gradient-dependent plasticity, the consistency condition, which results in a differential equation with respect to the plastic multiplier, is solved simultaneously with the equilibrium equation.
Chen, G., Baker, Graham
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FEBS Letters, EarlyView.Antimicrobial resistance (AMR) is of huge importance, resulting in over 1 million deaths each year. Here, we describe how a new drug, enmetazobactam, designed to help fight resistant bacterial diseases, inhibits a key enzyme (GES‐1) responsible for AMR. Our data show it is a more potent inhibitor than the related tazobactam, with high‐level computation
Michael Beer +10 more
wiley +1 more source
Silva Fennica, 2006 The purpose of this study was to investigate the vertical dependence of the basic density of Scots pine, Norway spruce, and birch stems, and how such dependence could be applied for determining the average stem wood density.
Repola, Jaakko
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Boundary Value Problems, 2020 In our paper we address the thermoelasticity theory of the strain gradient. First, we define the mixed problem with initial and boundary data in this context.
Marin Marin, Sorin Vlase, Ioan Tuns
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FEBS Letters, EarlyView.Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona +4 more
wiley +1 more source
Resonant optical gradient force interaction for nano-imaging and -spectroscopy
New Journal of Physics, 2016 The optical gradient force provides optomechanical interactions, for particle trapping and manipulation, as well as for near-field optical imaging in scanning probe microscopy.
Honghua U Yang, Markus B Raschke
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FEBS Letters, EarlyView.Angiotensin II (AngII), a neuropeptide, interacts with amyloid‐β (Aβ), a key player in Alzheimer's disease. This study reveals that AngII reduces Aβ aggregation and membrane disruption in vitro. Biophysical assays and molecular modeling suggest AngII binds disordered Aβ forms, potentially modulating early amyloidogenic events and contributing to ...
Mohsen Habibnia +5 more
wiley +1 more source
FEBS Letters, EarlyView.Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer +7 more
wiley +1 more source