Results 71 to 80 of about 3,311,038 (365)

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Torque-operated gradient-index axicon

, 2013
We describe a gradient-index axicon based on twisting of crystals. We demonstrate that the focal length of the axicon can be efficiently operated by the torsion moment.
Skab, Ihor, Smyk, Mykola, Vasylkiv, Yurij, Vlokh, Rostyslav   +3 more
core   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Systems of quasilinear elliptic equations with dependence on the gradient via subsolution-supersolution method

, 2017
For the homogeneous Dirichlet problem involving a system of equations driven by \begin{document}$(p,q)$\end{document} -Laplacian operators and general gradient dependence we prove the existence of solutions in the ordered rectangle determined by a ...
D. Motreanu, C. Vetro, F. Vetro
semanticscholar   +1 more source

Analytical Solution of the O-X Mode Conversion Problem

, 2010
The excitation of a slow extraordinary wave in a overdense plasma from an ordinary wave impinging on the critical layer in the plane spanned by the density gradient and magnetic field is solved analytically by formulating the problem in terms of a ...
Abramowitz, Budden, Cairns, Francesco Volpe, Ginzburg, Gospodchikov, Hansen, Köhn, Laqua, Laqua, Laqua, Laqua, Maekawa, Mjølhus, Podoba, Popov, Popov, Preinhaelter, Shevchenko, Stix, Swanson, Volpe, Weitzner, Weitzner, Zwillinger, Zwillinger   +25 more
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Synthetic Oversampling Method Based Noiseless Gradient Distribution [PDF]

Jisuanji kexue
Synthetic Oversampling Method is an important means to solve imbalanced classification problem,but the current oversampling methods still have many problems when dealing with high-dimensional imbalanced classification problem.A synthetic oversampling ...
HU Libin, ZHANG Yunfeng, LIU Peide
doaj   +1 more source

Laplacian-level density functionals for the exchange-correlation energy of low-dimensional nanostructures

, 2010
In modeling low-dimensional electronic nanostructures, the evaluation of the electron-electron interaction is a challenging task. Here we present an accurate and practical density-functional approach to the two-dimensional many-electron problem.
Pittalis, S., Rasanen, E.
core   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

The mixed problem in the theory of strain gradient thermoelasticity approached with the Lagrange identity

Boundary Value Problems, 2020
In our paper we address the thermoelasticity theory of the strain gradient. First, we define the mixed problem with initial and boundary data in this context.
Marin Marin, Sorin Vlase, Ioan Tuns
doaj   +1 more source