Results 71 to 80 of about 3,703,082 (328)
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Solvability of quasilinear elliptic equations with strong dependence on the gradient
We study the problem of existence of positive, spherically symmetric strong solutions of quasilinear elliptic equations involving p-Laplacian in the ball. We allow simultaneous strong dependence of the right-hand side on both the unknown function and its
Darko Žubrinić
doaj +1 more source
Pomeranchuk effect and spin-gradient cooling of Bose-Bose mixtures in an optical lattice
We theoretically investigate finite-temperature thermodynamics and demagnetization cooling of two-component Bose-Bose mixtures in a cubic optical lattice, by using bosonic dynamical mean field theory (BDMFT).
A. Auerbach +5 more
core +1 more source
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Numerical Study of Drop Motion on a Surface with Wettability Gradient and Contact Angle Hysteresis
In this work, the motion of a 2-D drop on a surface with given wettability gradient is studied numerically by a hybrid lattice-Boltzmann finite-difference method using the multiple-relaxation-time collision model.
Huang, Haibo +2 more
core +1 more source
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Synthetic Oversampling Method Based Noiseless Gradient Distribution [PDF]
Synthetic Oversampling Method is an important means to solve imbalanced classification problem,but the current oversampling methods still have many problems when dealing with high-dimensional imbalanced classification problem.A synthetic oversampling ...
HU Libin, ZHANG Yunfeng, LIU Peide
doaj +1 more source
Torque-operated gradient-index axicon
We describe a gradient-index axicon based on twisting of crystals. We demonstrate that the focal length of the axicon can be efficiently operated by the torsion moment.
Skab, Ihor +3 more
core +1 more source
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source

