Results 71 to 80 of about 36,010,976 (311)
The gradient discretisation method for linear advection problems [PDF]
, 2019 We adapt the Gradient Discretisation Method (GDM), originally designed for elliptic and parabolic partial differential equations, to the case of a linear scalar hyperbolic equations.
Droniou, Jérôme +3 more
core +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Remote Sensing, 2020 Atmospheric boundary layer height (ABLH) was observed by the CHM15k ceilometer (January 2008 to October 2013) and the PollyXT lidar (July 2013 to December 2018) over the European Aerosol Research LIdar NETwork to Establish an Aerosol Climatology ...
Dongxiang Wang +4 more
doaj +1 more source
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Gradient method with AFEM for parameter-estimation
Selecciones Matemáticas, 2023 We consider the adaptive finite element discretization of parameter estimation problems for nonlinear elliptic partial differential equations. The idea is to use a gradient method on the finite-dimensional parameter space for the minimization of the ...
Roland Becker
doaj +1 more source
Regularized Dual Averaging Image Reconstruction for Full-Wave Ultrasound Computed Tomography
, 2017 Ultrasound computed tomography (USCT) holds great promise for breast cancer screening. Waveform inversion-based image reconstruction methods account for higher order diffraction effects and can produce high-resolution USCT images, but are computationally
Anastasio, Mark A. +4 more
core +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
The Average Sentinel of the Heat Equation with an Unknown Reaction
AxiomsIn this paper, we analyze the identification of the amount of pollutant discharged problem by each source in a heat system when the dynamics of the state are governed by a parameterized unknown operator.
Houria Selatnia +2 more
doaj +1 more source
A Family of Gradient Methods for Optimization [PDF]
The Computer Journal, 1970 The approaches to the problem of maximising or minimising a nonlinear function of several variables can be put into three categories according to how much information is extracted from the function. 1. Only the function value. The more well-known methods in this category are those of Nelder and Mead (1965), Powell (1965), Rosenbrock (1960), and Swann ...
openaire +1 more source
Polynomial Preconditioning for Gradient Methods
CoRR, 2023 We study first-order methods with preconditioning for solving structured nonlinear convex optimization problems. We propose a new family of preconditioners generated by symmetric polynomials. They provide first-order optimization methods with a provable improvement of the condition number, cutting the gaps between highest eigenvalues, without explicit ...
Nikita Doikov, Anton Rodomanov
openaire +3 more sources