Results 61 to 70 of about 632,931 (308)

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

ESTIMATION OF THE CONCRETE PAVEMENT TEMPERATURE FIELDS AND THEIR GRADIENTS

Известия высших учебных заведений и энергетических объединенний СНГ: Энергетика, 2015
The heat fluxes impact on the road-dressing concrete surfacing under different regions climatic conditions of the construction and maintenance dramatically degrades their solidity, corroding-, shiftingand frost-resistance, and ultimately – the service ...
M. K. Pshembaev, Ya. N. Kovalev, V. D. Akelyev   +2 more
doaj  

Controlled Preparation of Nanoparticle Gradient Materials by Diffusion

Nanomaterials, 2019
Nanoparticle gradient materials combine a concentration gradient of nanoparticles with a macroscopic matrix. This way, specific properties of nanoscale matter can be transferred to bulk materials.
Andreas Spinnrock, Max Martens, Florian Enders, Klaus Boldt, Helmut Cölfen   +4 more
doaj   +1 more source

Signal diffusion along connectome gradients and inter-hub routing differentially contribute to dynamic human brain function

NeuroImage, 2021
Human cognition is dynamic, alternating over time between externally-focused states and more abstract, often self-generated, patterns of thought. Although cognitive neuroscience has documented how networks anchor particular modes of brain function ...
Bo-yong Park, Reinder Vos de Wael, Casey Paquola, Sara Larivière, Oualid Benkarim, Jessica Royer, Shahin Tavakol, Raul R. Cruces, Qiongling Li, Sofie L. Valk, Daniel S. Margulies, Bratislav Mišić, Danilo Bzdok, Jonathan Smallwood, Boris C. Bernhardt   +14 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

A portfolio approach to managing ecological risks of global change

Ecosystem Health and Sustainability, 2017
The stressors of global environmental change make it impossible over the long term for natural systems to maintain their historical composition. Conservation's new objective must be to maintain the building blocks of future systems (e.g., species, genes,
Gregory H. Aplet, Peter S. Mckinley
doaj   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Optimal and Efficient Approximations of Gradients of Functions with Nonindependent Variables

Axioms
Gradients of smooth functions with nonindependent variables are relevant for exploring complex models and for the optimization of the functions subjected to constraints. In this paper, we investigate new and simple approximations and computations of such
Matieyendou Lamboni
doaj   +1 more source