Cutaneous graft-versus-host disease after hematopoietic stem cell transplant - a review [PDF]
Graft-versus-host disease (GVHD) is a major complication of allogeneic hematopoietic stem cell transplants (allo-HSCT) associated with significant morbidity and mortality. The earliest and most common manifestation is cutaneous graft-versus-host disease.
Cesar Daniel Villarreal Villarreal+3 more
doaj +5 more sources
Overlap subtype of chronic graft-versus-host disease is associated with an adverse prognosis, functional impairment, and inferior patient-reported outcomes: a Chronic Graft-versus-Host Disease Consortium study [PDF]
Background The National Institutes of Health Consensus Conference proposed the term “overlap” graft-versus-host disease to describe the situation when both acute and chronic graft-versus-host disease are present.Design and Methods We examined whether the
Joseph Pidala+12 more
doaj +4 more sources
Beta herpes viruses in patients with cutaneous graft-versus-host disease [PDF]
Graft-versus-host disease is a major complication of allogenic bone marrow transplantation. Beta herpes viruses’ role in pathogenesis and prognosis of graft-versus-host disease is significant.
V. V. Baykov+6 more
doaj +3 more sources
Novel regulatory therapies for prevention of Graft-versus-host disease [PDF]
Graft-versus-host disease is one of the major transplant-related complications in allogeneic hematopoietic stem cell transplantation. Continued efforts have been made to prevent the occurrence of severe graft-versus-host disease by eliminating or ...
Leventhal Joseph+4 more
doaj +4 more sources
Expression of a dominant T-cell receptor can reduce toxicity and enhance tumor protection of allogeneic T-cell therapy [PDF]
Due to the lack of specificity for tumor antigens, allogeneic T-cell therapy is associated with graft-versus-host disease. Enhancing the anti-tumor specificity while reducing the graft-versus-host disease risk of allogeneic T cells has remained a ...
Angelika Holler+9 more
doaj +5 more sources
Improved survival after acute graft-versus-host disease diagnosis in the modern era [PDF]
A cute graft-versus-host disease remains a major threat to a successful outcome after allogeneic hematopoietic cell transplantation. While improvements in treatment and supportive care have occurred, it is unknown whether these advances have resulted in ...
Hanna J. Khoury+46 more
doaj +3 more sources
Antilymphocyte globulin for matched sibling donor transplantation in patients with myelofibrosis [PDF]
The use of antihuman T-lymphocyte immunoglobulin in the setting of transplantation from an HLA-matched related donor is still much debated. Acute and chronic graft-versus-host disease are the main causes of morbidity and mortality after allogeneic ...
Marie Robin+26 more
doaj +10 more sources
Does minor histocompatibility antigen HA-1 disparity affect the occurrence of graft-versus-host disease in tunisian recipients of hematopoietic stem cells? [PDF]
INTRODUCTION: Minor histocompatibility antigen HA-1 (MiHAg-HA-1) disparity between a patient and his or her human leukocyte antigen (HLA) genoidentical donor has been widely associated with an increased risk of graft-versus-host disease following ...
Mohamed Hichem Sellami+7 more
doaj +6 more sources
Graft-versus-lymphoma effect in a 64-year-old caucasian woman after allogeneic stem-cell transplantation: a case report [PDF]
Introduction The existence of a graft-versus-lymphoma effect is well established. When lacking a firm diagnosis, however, the clinician is challenged to to weigh the potential benefits of the graft-versus-lymphoma effect against potential dangers of ...
Behre Gerhard+3 more
doaj +4 more sources
Minimal change nephrotic syndrome after stem cell transplantation: a case report and literature review [PDF]
Graft-versus-host disease is one of the most frequent complications occurring after haematopoietic stem cell transplantation. Recently, renal involvement has been described as a manifestation of chronic graft-versus-host disease.
Silva Sandra+7 more
doaj +3 more sources