Results 61 to 70 of about 179,002 (365)

Clinical and Dermoscopic Evaluation of Melanocytic Lesions in Patients with Chronic Graft Versus Host Disease [PDF]

, 2020
Patients treated with haematopoietic stem cell transplantation are at increased risk of cutaneous malignant neoplasms. There are no reports on the characteristics of melanocytic lesions in patients with chronic graft versus host disease and the value of ...
Alós i Hernández, Llúcia, Barreiro Capurro, Alicia, Carrera Álvarez, Cristina, Galindo, Beatriz Alejo, Giavedoni, Priscila, Malvehy, J. (Josep), Mascaró Galy, José Manuel, Puig i Sardà, Susana   +7 more
core  

Oral chronic graft-versus-host disease: analysis of dendritic cells subpopulations [PDF]

Anais Brasileiros de Dermatologia, 2014
The graft-versus-host disease is the major cause of morbidity and mortality in patients who have undergone hematopoietic stem cell transplantation. Aiming at contributing to the understanding of the role of myeloid and plasmacytoid dendritic cells, and ...
Clara Marino Espricigo Botari, Adauto José Ferreira Nunes, Mair Pedro de Souza, Érica Sinara Lenharo Orti-Raduan, Ana Gabriela Salvio   +4 more
doaj   +2 more sources

Mixture of Input-Output Hidden Markov Models for Heterogeneous Disease Progression Modeling [PDF]

arXiv, 2022
A particular challenge for disease progression modeling is the heterogeneity of a disease and its manifestations in the patients. Existing approaches often assume the presence of a single disease progression characteristics which is unlikely for neurodegenerative disorders such as Parkinson's disease.
arxiv  

The use of FK-506 for small intestine llotransplantation: Inhibition of acute rejection and prevention of fatal graft-versus-host disease [PDF]

, 1990
Small intestine allotransplantation in humans is not yet feasible due to the failure of the current methods of immunosuppression. FK-506, a powerful new immunosuppressive agent that is synergistic with cyclosporine, allows long-term survival of ...
Banner, B, Cai, X, Cramer, DV, Hoffman, AL, Makowka, L, Pascualone, A, Starzl, TE, Todo, S   +7 more
core   +1 more source

Robust acute myeloid leukemia engraftment in humanized scaffolds using injectable biomaterials and intravenous xenotransplantation

Molecular Oncology, Volume 19, Issue 5, Page 1371-1385, May 2025.
Patient‐derived xenografts (PDXs) can be improved by implantation of a humanized niche. We tested different biomaterials and approaches, and demonstrate that the combination of an injectable biomaterial for scaffold creation plus an intravenous route for acute myeloid leukemia (AML) xenotransplantation provide the most convenient and robust approach to
Daniel Busa, Zdenka Herudkova, Jan Hyl, Jakub Vlazny, Filip Sokol, Kvetoslava Matulova, Adam Folta, Jakub Hynst, Lucy Vojtova, Leos Kren, Martin Repko, Zdenek Racil, Jiri Mayer, Martin Culen   +13 more
wiley   +1 more source

The pathology of bone marrow transplantation in Hong Kong Chinese [PDF]

, 1996
The pathological lesions found in 68 successfully engrafted patients with human leucocyte antigen-matched sibling-related bone marrow transplants werereviewed retrospectively.
Chan, KW, Chiu, EKW, Ng, IOL, Shek, TWH
core  

Molecular and computational diagnostic approach identifies FOXP3, ICOS, CD52 and CASP1 as the most informative biomarkers in acute graft versus host disease. [PDF]

, 2012
BACKGROUND: Acute graft-versus-host disease is a severe complication of allogeneic stem cell transplantation in which the functional immune cells of the donor recognize the recipient as foreign and mount an immunological attack.
Console, G., Cuzzola, M., Fedele, R., Fiasche&apos, Iacopino, P., Irrera, G., Martino, M., Massi, Daniela, Messina, G., Morabito, F., Recchia, A. G.   +10 more
core   +1 more source

Stroma gene signature predicts responsiveness to chemotherapy in pancreatic ductal adenocarcinoma patient‐derived xenograft models

Molecular Oncology, Volume 19, Issue 4, Page 1075-1091, April 2025.
Pancreatic ductal adenocarcinoma patient‐derived xenografts (PDAC‐PDXs) engrafted orthotopically in the pancreas of immunodeficient mice retain the main genetic and histopathological characteristics of the original human tumors. A 294 stroma gene signature differentiates between PDAC‐PDXs that are responsive to gemcitabine plus nab‐paclitaxel versus ...
Alessia Anastasia, Laura Formenti, Paola Ostano, Lucia Minoli, Andrea Resovi, Lavinia Morosi, Claudia Fioravanti, Edoardo Micotti, Cristina Matteo, Eugenio Scanziani, Giovanna Chiorino, Raffaella Giavazzi, Carmen Ghilardi, Dorina Belotti   +13 more
wiley   +1 more source

Inhibition of protein geranylgeranylation and farnesylation protects against graft-versus-host disease via effects on CD4 effector T cells

Haematologica, 2013
Despite advances in immunosuppressive regimens, acute graft-versus-host disease remains a frequent complication of allogeneic hematopoietic cell transplantation.
Anne-Kathrin Hechinger, Kristina Maas, Christoph Dürr, Franziska Leonhardt, Gabriele Prinz, Reinhard Marks, Ulrike Gerlach, Maike Hofmann, Paul Fisch, Jürgen Finke, Hanspeter Pircher, Robert Zeiser   +11 more
doaj   +1 more source

The Effect of Disease-induced Mortality on Structural Network Properties [PDF]

PLoS ONE, 10, e0136704 (2015), 2015
As the understanding of the importance of social contact networks in the spread of infectious diseases has increased, so has the interest in understanding the feedback process of the disease altering the social network. While many studies have explored the influence of individual epidemiological parameters and/or underlying network topologies on the ...
arxiv   +1 more source