Results 11 to 20 of about 105,303 (279)

The IL-12 Cytokine and Receptor Family in Graft-vs.-Host Disease

open access: yesFrontiers in Immunology, 2019
Allogeneic hematopoietic cell transplantation (allo-HCT) is performed with curative intent for high- risk blood cancers and bone marrow failure syndromes; yet the development of acute and chronic graft-vs.-host disease (GVHD) remain preeminent causes of ...
David Bastian   +4 more
doaj   +2 more sources

AAV-mediated expression of HLA-G for the prevention of experimental ocular graft vs. host disease [PDF]

open access: yesMolecular Therapy: Methods & Clinical Development, 2023
Ocular graft versus host disease (OGvHD) develops after allogeneic hematopoietic stem cell transplantation (HSCT) and manifests as ocular surface inflammatory disease.
Jacob P. Nilles   +8 more
doaj   +2 more sources

Treatment of Severe Steroid-Refractory Acute-Graft-vs.-Host Disease With Mesenchymal Stem Cells–Single Center Experience

open access: yesFrontiers in Bioengineering and Biotechnology, 2018
The most effective treatment of steroid refractory acute graft vs. host disease (aGvHD) is not yet established and mesenchymal stem cells (MSC) appear to be a promising therapy for the condition. We report single center case series of three patients, who
Maja Česen Mazič   +4 more
doaj   +2 more sources

FRI100 Lipoprotein X In Graft Vs. Host Disease Affecting Liver [PDF]

open access: goldJ Endocr Soc, 2023
Deepak Vedamurthy   +4 more
europepmc   +2 more sources

Evaluation of Ruxolitinib for Steroid-Refractory Chronic Graft-vs-Host Disease After Allogeneic Hematopoietic Stem Cell Transplantation

open access: yesJAMA Network Open, 2021
Key Points Question Is ruxolitinib an option for patients with steroid-refractory chronic graft-vs-host disease, and what characteristics are associated with treatment response?
Hengwei Wu   +10 more
semanticscholar   +1 more source

Immunomodulatory Effects of Histone Deacetylation Inhibitors in Graft-vs.-Host Disease After Allogeneic Stem Cell Transplantation

open access: yesFrontiers in Immunology, 2021
Histone deacetylase inhibitors are currently the most studied drugs because of their beneficial effects on inflammatory response. Emerging data from numerous basic studies and clinical trials have shown that histone deacetylase inhibitors can suppress ...
Xiaoxiao Xu   +3 more
semanticscholar   +1 more source

Therapeutic Potential of a Senolytic Approach in a Murine Model of Chronic GVHD

open access: yesBiology, 2023
Graft-versus-host disease (GVHD) is a life-threatening systemic complication of allogeneic hematopoietic stem cell transplantation (HSCT) characterized by dysregulation of T and B cell activation and function, scleroderma-like features, and multi-organ ...
Deepika Raman   +7 more
doaj   +1 more source

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