Results 21 to 30 of about 105,303 (279)

Calcineurin inhibitors suppress acute graft-vs-host disease via NFAT-independent inhibition of T cell receptor signaling.

Journal of Clinical Investigation, 2021
Inhibitors of calcineurin phosphatase activity (CNIs) such as cyclosporin A (CsA) are widely used to treat tissue transplant rejection and acute graft-versus-host disease (aGVHD), for which inhibition of NFAT-dependent gene expression is the mechanistic ...
S. Otsuka, N. Melis, M. Gaida, D. Dutta, R. Weigert, J. Ashwell   +5 more
semanticscholar   +1 more source

Role of HRCT Chest in Post Stem Cell Transplant Recipients Suspected of Pulmonary Complications [PDF]

Journal of Clinical and Diagnostic Research, 2016
Introduction: Stem cell transplantation is today’s procedure of choice for management of various hematopoietic malignant and severe immunogenic disorders. High Resolution Computed Tomography (HRCT) is a common technique for the diagnosis of pulmonary
Abhishek Dwivedi, R Ravi Kumar, Ajay Sharma, S K Pannu   +3 more
doaj   +1 more source

Small Bowel Perforation Associated With Gastrointestinal Graft-Versus-Host Disease and Cytomegalovirus Enteritis in a Patient With Leukemia: A Case Report With Literature Review [PDF]

Annals of Coloproctology, 2020
Gastrointestinal graft-versus-host disease (GVHD) is a common complication after hematopoietic stem cell transplantation. Concomitant cytomegalovirus (CMV) enteritis worsens the prognosis of this condition.
Kwang-Seop Song, Min Jung Kim, Han-Ki Lim, Yoon Hwa Hong, Sung Sil Park, Chang Won Hong, Sung Chan Park, Dae Kyung Sohn, Kyung Su Han, Jae Hwan Oh   +9 more
doaj   +1 more source

Rehabilitation in Children With Sclerodermoid Chronic Graft-Versus-Host Disease: Case Series [PDF]

Annals of Rehabilitation Medicine, 2019
Joint contracture in chronic graft-versus-host disease (cGVHD) is refractory to treatment, and tends to deteriorate gradually over time. There is scant clinical research focusing on timing and intensity of rehabilitation on joint contractures in children
Minji Jung, In Young Sung, Eun Jae Ko
doaj   +1 more source

Umbilical cord blood transplantation: Still growing and improving

Stem Cells Translational Medicine, 2021
Umbilical cord blood transplantation (UCBT) has been performed in the clinic for over 30 years. The biological and immunological characteristics of umbilical cord blood (UCB) have been re‐recognized in recent years.
Xiaoyu Zhu, Baolin Tang, Zimin Sun
doaj   +1 more source

Acetabular Insufficiency Fractures in the Setting of Graft vs Host Disease: A Report of Two Cases

Arthroplasty Today, 2021
We report a case series of 2 patients with unilateral acetabular insufficiency fractures who received allogeneic peripheral blood stem cell transplantation for hematologic malignancies complicated by chronic graft vs host disease. These were managed with
Warren Nielsen, BS, Kathryn Schabel, MD
doaj   +1 more source

Brazilian workshop model to train investigators in chronic graft-versus-host disease clinical trials according to the 2005-2006 National Institutes of Health recommendations

Revista Brasileira de Hematologia e Hemoterapia, 2011
BACKGROUND: The lack of standardization of clinical diagnostic criteria, classification and severity scores of chronic graft-versus-host disease led the National Institutes of Health to propose consensus criteria for the purpose of clinical trials ...
Rita de Cássia Barbosa da Silva Tavares, Márcia de Matos Silva, Luis Fernando da Silva Bouzas, Maria Cláudia Rodrigues, Afonso Celso Vigorito, Vaneusa Funke, Marcos Mauad, Maria Elvira Pizzigatti Correa, Clarissa Vasconcellos de Souza, Elenaide Nunes, Alessandra Ferrari, Ariana Paixão, Talita Martins, Érika Pallottino, Mary Evelyn Dantas Flowers   +14 more
doaj   +1 more source

Senescence‐associated secretory phenotype promotes chronic ocular graft‐vs‐host disease in mice and humans

The FASEB Journal, 2020
Chronic graft‐vs‐host disease (cGVHD) is a multifactorial inflammatory disease that affects patients undergoing hematopoietic stem cell transplantation.
Mio Yamane, Shinri Sato, Eisuke Shimizu, S. Shibata, Motoshi Hayano, T. Yaguchi, H. Kamijuku, Mamoru Ogawa, Takanori Suzuki, S. Mukai, S. Shimmura, H. Okano, T. Takeuchi, Y. Kawakami, Y. Ogawa, K. Tsubota   +15 more
semanticscholar   +1 more source

Post-transplant cyclophosphamide versus anti-thymocyte globulin as graft- versus-host disease prophylaxis in haploidentical transplant

Haematologica, 2017
Severe graft-versus-host disease is a major barrier for non-T-cell-depleted haploidentical stem cell transplantation. There is no consensus on the optimal graft-versus-host disease prophylaxis.
Annalisa Ruggeri, Yuqian Sun, Myriam Labopin, Andrea Bacigalupo, Francesca Lorentino, William Arcese, Stella Santarone, Zafer Gülbas, Didier Blaise, Giuseppe Messina, Ardeshi Ghavamzadeh, Florent Malard, Benedetto Bruno, Jose Luis Diez-Martin, Yener Koc, Fabio Ciceri, Mohamad Mohty, Arnon Nagler   +17 more
doaj   +1 more source

Macrophage regulation of graft-vs-host disease

World Journal of Clinical Cases, 2020
Hematopoietic stem cell transplantation has become a curative choice of many hematopoietic malignancy, but graft-vs-host disease (GVHD) has limited the survival quality and overall survival of hematopoietic stem cell transplantation. Understanding of the
Yaqun Hong, Bo Wan, Xiao-Fan Li
semanticscholar   +1 more source