Results 171 to 180 of about 1,098,781 (385)
Advanced Science, EarlyView.Design of neurophilic biomimetic lipoprotein for intracerebral delivery of nerve growth factor (NGF) to traumatic brain injury (TBI). Nc‐rHDL@P can cross the BBB through ApoE3‐receptors interaction and target neurons via αRDP‐nAChR interaction. Nc‐rHDL@P delivers NGF to the lesion sites, rescues neurons, curbs inflammation, boosts sensorimotor and ...
Jialin Huang +21 more
wiley +1 more source
Rejection of human intestinal allografts: Alone or in combination with the liver [PDF]
, 1994 The current results of the present series demonstrate that intestinal allografts are more vulnerable to rejection and continue to be at a significantly higher risk long after transplantation compared with isolated liver allograft recipients. Unexpectedly,
Abu-Elmagd, K +12 more
core
Engraftment, Graft Failure, and Rejection
, 2017 AbstractEngraftment following HSCT is an essential goal for sustained long-term and effective hematopoiesis. It is the most important criteria for a better overall survival. However, stem cell engraftment may be accompanied with a clinical condition known as engraftment syndrome (ES) that could have a devastating outcome.
openaire +2 more sources
Centimeter‐Scale Self‐Assembling Tendon Organoids Drive Tissue Regeneration
Advanced Science, EarlyView.Centimeter‐scale tendon organoids are engineered by mimicking the extracellular matrix and optimizing chemical cues to guide tendon stem/progenitor cells. These large, self‐assembling constructs overcome conventional size limitations and exhibit enhanced tenogenic differentiation, extracellular matrix production, and mechanical resilience. Their tissue‐
Tianshun Fang +16 more
wiley +1 more source
Randomized preclinical study of machine perfusion in vascularized composite allografts
BJS (British Journal of Surgery), EarlyView., 2020 This study was designed to identify the optimum machine perfusion parameters for preservation of limbs before transplantation, and determine whether this was better than cold storage. Normothermic machine perfusion at a pressure of 70 mmHg (NMP‐70) provided superior preservation to cold storage after transplantation.
K. R. Amin +7 more
wiley +1 more source
Advanced Science, EarlyView.This study reveals that ARID3A in macrophages can transcriptionally regulate the THBS1‐CD47 axis after heart transplantation (HT), thereby inducing activated neutrophils to release NETs through the p38 MAPK signaling pathway. The itaconate derivative 4‐OI can inhibit ARID3A in macrophages and promote the accumulation of antioxidant factors, thereby ...
Hao Tian +7 more
wiley +1 more source
Evidence for hyperacute rejection of human liver grafts: The case of the canary kidneys [PDF]
, 1989 Thomas E. Starzl +9 more
openalex +1 more source
Laeverin is Cell‐Surface Target for Liquid‐Phase Metastasizing Cancer Cells
Advanced Science, EarlyView.This study revealed that epithelial cancer cells in the floating phase induce the expression of laeverin (LVRN) that is a trophoblast‐specific and cell‐surface immunoregulatory factor and showed that anti‐LVRN ADC is a promising agent that can attack cancer cells in the metastatic liquid phase and block further distant metastasis.
Haruki Kasama +17 more
wiley +1 more source