Results 61 to 70 of about 1,098,781 (385)

Characteristics of endothelial corneal transplant rejection following immunisation with SARS-CoV-2 messenger RNA vaccine

British Journal of Ophthalmology, 2021
Aim We report two cases of endothelial corneal allograft rejection following immunisation with SARS-CoV-2 messenger RNA (mRNA) vaccine BNT162b2 and describe the implications for management of transplant recipients postvaccination for COVID-19.
Maria Phylactou, Ji-Peng Olivia Li, D. Larkin   +2 more
semanticscholar   +1 more source

Lack of Association between Interleukin-10 Gene Polymorphisms and Graft Rejection Risk in Kidney Transplantation Recipients: A Meta-Analysis. [PDF]

PLoS ONE, 2015
Interleukin-10 (IL-10) is an important immunomodulatory cytokine. Several studies focused the association between IL-10 promoter gene polymorphisms and graft rejection risk in kidney transplantation recipients.
Jiachuan Xiong, Yiqin Wang, Ying Zhang, Ling Nie, Daihong Wang, Yunjian Huang, Bing Feng, Jingbo Zhang, Jinghong Zhao   +8 more
doaj   +1 more source

Hemostasis caused by stent-graft insertion followed by graft removal for pancreas graft bleeding due to chronic rejection: A case report

Transplantation Reports, 2022
Introduction: Lethal symptoms due to graft rejection warrant rapid removal of the transplanted graft to save the patient's life. We report a case of massive pancreas graft bleeding due to chronic rejection that necessitated graft removal after hemostasis
Kohei Miura, Takashi Kobayashi, Hirosuke Ishikawa, Seiji Saito, Yasuo Obata, Yohei Miura, Koji Toge, Yuki Hirose, Taku Ohashi, Kazuyasu Takizawa, Jun Sakata, Masayuki Tasaki, Kazuhide Saito, Yoshihiko Tomita, Toshifumi Wakai   +14 more
doaj   +1 more source

Current trends in single‐cell RNA sequencing applications in diabetes mellitus

FEBS Open Bio, EarlyView.
Single‐cell RNA sequencing is a powerful approach to decipher the cellular and molecular landscape at a single‐cell resolution. The rapid development of this technology has led to a wide range of applications, including the detection of cellular and molecular mechanisms and the identification and introduction of novel potential diagnostic and ...
Seyed Sajjad Zadian, Khodakaram Jahanbin, Shekoofeh Nikooei, Marzieh Rostaminejad, Arezoo Rahimi, Pedram Abdizadeh, Behnam Alipoor   +6 more
wiley   +1 more source

Chronic allograft rejection: A significant hurdle to transplant success

Burns & Trauma, 2014
The state-of-the-art immunosuppression drugs do not ensure indefinite transplant survival, and most transplants are continuously lost to chronic rejection even years posttransplantation.
Malgorzata Kloc, Rafik M Ghobrial
doaj   +1 more source

Graft-infiltrating host dendritic cells play a key role in organ transplant rejection

Nature Communications, 2016
Successful engraftment of organ transplants has traditionally relied on preventing the activation of recipient (host) T cells. Once T-cell activation has occurred, however, stalling the rejection process becomes increasingly difficult, leading to graft ...
Quan Zhuang, Quan Liu, S. Divito, Q. Zeng, Karim M Yatim, A. D. Hughes, Darling M. Rojas-Canales, A. Nakao, W. Shufesky, Amanda L. Williams, Rishab Humar, R. Hoffman, W. Shlomchik, M. Oberbarnscheidt, Fadi G Lakkis, A. Morelli   +15 more
semanticscholar   +1 more source

Development and Preliminary In Vivo Study of 3D‐Printed Bioactive Glass Scaffolds with Trabecular Architecture

Advanced Engineering Materials, EarlyView.
This study reports the fabrication of trabecular bioactive glass scaffolds (composition “1d”: 46.1SiO2‐28.7CaO‐8.8MgO‐6.2P2O5‐5.7CaF2‐4.5Na2O wt%) through vat photopolymerization and the relevant results from mechanical testing and in vivo implantation procedures in rabbit femora, showing great promise for bone tissue engineering applications.
Dilshat Tulyaganov, Roberta Gabrieli, Avzal Akbarov, Nigora Nigmatova, Bekhzod Khabilov, Alessandro Schiavi, Martin Schwentenwein, Enrica Verné, Francesco Baino   +8 more
wiley   +1 more source

NK Cells: Not Just Followers But Also Initiators of Chronic Vascular Rejection

Transplant International
Chronic graft rejection represents a significant threat to long-term graft survival. Early diagnosis, understanding of the immunological mechanisms and appropriate therapeutic management are essential to improve graft survival and quality of life for ...
Mathilde Chambon, Alice Koenig, Alice Koenig, Alice Koenig   +3 more
doaj   +1 more source

Reduced CD40L expression on ex vivo activated CD4+T-lymphocytes from patients with excellent renal allograft function measured with a rapid whole blood flow cytometry procedure [PDF]

, 2004
Background: The CD40-CD40L (CD154) costimulatory pathway plays a critical role in the pathogenesis of kidney allograft rejection. In renal transplant biopsies, CD4+ CD40L+ graft-infiltrating cells were detected during chronic rejection in contrast to ...
Friedrich, N., Gruber, R., Landgraf, R., Lederer, Stephan R., Sitter, Thomas, Toepfer, Marcel   +5 more
core   +1 more source

Adalimumab‐Poloxamer Conjugate for Bio‐Better: Enhanced Stability and Function

Advanced Functional Materials, EarlyView.
Antibody‐polymer conjugates, particularly poloxamer conjugates, enhance antibody stability by improving tolerance to physicochemical stress and attenuating proteolysis by proteases. Furthermore, the higher affinity observed with poloxamer conjugation compared to standard PEGylation results in improved therapeutic efficacy in rheumatoid arthritis mouse ...
Jaewon Roh, Sanghee Lee, Soomin Cho, Kun Na   +3 more
wiley   +1 more source