Results 91 to 100 of about 43,427 (259)
Atypical early follicular graft-vs-host disease
Follicular graft-vs-host disease (GVHD) was probably first reported in 1984.1 Clinically acute follicular GVHD was described as an eruption similar to a bacterial or fungal folliculitis following allogenic bone marrow transplantation (BMT).2 Cases of ...
Goiriz, Rebeca
core
Pathophysiologic mechanisms of acute graft-vs.-host disease
, 1999 Graft-vs.-host disease (GVHD) remains the major toxicity of allogeneic bone marrow transplantation. Mechanistic studies in experimental animal models provide a better understanding of the complex relationships and cascade of events mediated by cellular ...
Ferrara, James L.M +4 more
core +1 more source
Arthritis &Rheumatology, Accepted Article.Objective To characterize the clinical, immunologic, and proteomic changes associated with CD19 chimeric antigen receptor T‐cell therapy in patients with progressive systemic sclerosis. Methods Patients with progressive systemic sclerosis received CD19 CAR‐T cell therapy and were followed longitudinally for safety, clinical efficacy, immune ...
Chenhan Jia +16 more
wiley +1 more source
Histopathology of graft-vs-host disease of gastrointestinal tract and liver: An update
, 2016 © American Society for Clinical Pathology, 2016. All rights reserved. Objectives: Graft-vs-host disease (GVHD) is a donor T-cellmediated disorder affecting the recipient\u27s skin, gastrointestinal tract, lungs, and liver.
Sepulveda, Antonia +3 more
core +1 more source
Biologic Augmentation With Biocomposite Scaffold in Revision Quadriceps Tendon Repair
Arthroscopy Techniques, EarlyView.Abstract Quadriceps tendon rupture is a relatively uncommon injury, typically occurring in middle‐aged males, and is often associated with systemic comorbidities or trauma. Although primary repair techniques provide excellent outcomes when performed acutely, revision surgery presents unique challenges due to poor tissue quality and compromised ...
Cory N. Meixner +2 more
wiley +1 more source
Efficacy, safety and cost‐effectiveness of CAR‐T therapy
British Journal of Clinical Pharmacology, EarlyView.CAR T‐cells demonstrate high efficacy in blood cancers, including ALL, MM and DLBCL. Innovations target solid tumours despite challenges such as antigen escape. Combination therapies enhance the delivery and infiltration of CAR T cells. Toxicity, cost and resistance remain major barriers to clinical use.
Emina Karahmet Sher +7 more
wiley +1 more source
British Journal of Clinical Pharmacology, EarlyView.Aims The repurposed use of favipiravir in COVID‐19 has been reported to have limited clinical efficacy, yet it has been widely used in some countries. Favipiravir causes mutagenesis in RNA viruses, and it is currently unknown whether it may have a measurable effect on the virus in humans.
Akosua A. Agyeman +9 more
wiley +1 more source
Precision medicine in paediatrics: Progress and priorities
British Journal of Clinical Pharmacology, EarlyView.Precision medicine is revolutionizing personalized healthcare, advancing both diagnostics and therapeutics at an unprecedented pace. Reviewing the paediatric applications of pharmacometrics, pharmacogenomics and advanced therapy medicinal products highlights not only the relevance of these exciting innovations to frontline care but also the significant
Nicola Husain +3 more
wiley +1 more source
Graft-vs-Host Disease in a Liver Transplant Patient With COVID-19 Infection. [PDF]
ACG Case Rep J, 2023 Kiparizoska S, Nguyen V, Rangnekar AS.
europepmc +1 more source
Biomaterial design strategies for enhancing mitochondrial transplantation therapy
BMEMat, EarlyView.Biomaterials to facilitate mitochondrial transplantation therapy: biomaterials as barriers to protect mitochondria from pathophysiological microenvironments, like osmotic stress caused by the excessive concentration of calcium ion, reactive oxygen species, and advanced glycation end products; biomaterials integrating with biochemical cues to improve ...
Shaoyang Kang +12 more
wiley +1 more source