Results 91 to 100 of about 44,451 (302)
Management of Graft vs Host Disease Following Intestinal Transplantation [PDF]
, 2023 Purpose: We present four patients with multi-visceral transplant (MVT) complicated by graft-versus-host disease (GvHD). Methods: We reviewed 26 cases following MVT for incidence of GvHD.
Gupta, Deven +4 more
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Optimization of B Cell Responses in Human Immune System Mice Through Organoid Based Screening
Advanced Science, EarlyView.Human immune system (HIS) mice show limited B cell responses to immunization. Using HIS mouse spleen organoids, this study identifies cytokine combinations and innate immune signals that drive human B cell expansion, differentiation, and class‐switch. Applying these signals in vivo through temporal separation enables antigen‐specific IgG responses and ...
Haiqiao Sun +6 more
wiley +1 more source
Early And Late Oral Features Of Chronic Graft-versus-host Disease [PDF]
, 2015 Background: Chronic graft-versus-host disease is a serious complication of allogeneic hematopoietic cell transplantation, and the mouth is one of the affected sites. Objective: The aim of this study was to evaluate the oral features of this disease after
Torres S.R. +7 more
core +1 more source
Engineering Microbial Particles for Next‐Generation Biomedical Platforms
Advanced Science, EarlyView.Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li +7 more
wiley +1 more source
Cytokine Detection and Modulation in Acute Graft vs. Host Disease in Mice
Mediators of Inflammation, 1994 A murine model for acute lethal graft vs. host disease (GVHD) was used to study the role that a number of cytokines play in the development of lethal GVHD. In this study we focused on the role of IL-1, IL-2, IL-4, IL-6, IFN-γ and TNF-α.
A. C. Knulst +6 more
doaj +1 more source
Organoid Brain‐Machine‐Interface Devices for Central Nervous System Repair
Advanced Science, EarlyView.We envision organoid brain‐machine‐interface (Organoid‐BMI) devices as new biohybrid bidirectional communication pathways to connect the human CNS and the external world for personalized CNS repair and regeneration. ABSTRACT Central nervous system (CNS) repair and regeneration suffer from tremendous clinical challenges due to current limitations in ...
Yantao Xing +10 more
wiley +1 more source
Oral Involvement In Chronic Graft Versus Host Disease: A Prospective Study Of 19 Brazilian Patients [PDF]
, 2015 Chronic graft versus host disease (cGVHD) is the most common late complication of allogeneic bone marrow transplantation. The oral cavity is the most common site of cGVHD involvement.
Pereira C.M. +4 more
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Graft-vs-Host Disease following Allogeneic Hematopoietic Cell Transplantation [PDF]
, 2011 Background Allogeneic hematopoietic cell transplantation (HCT) is a potentially curative therapy with proven efficacy in the management of hematologic malignancies.
Joseph Pidala, Pidala, Joseph
core +1 more source
Advanced Science, EarlyView.A dual‐function cell‐free therapeutic based on DC2.4 cell‐derived exosomes engineered to display BCMA. (Left) Soluble Ligand Sequestration (Decoy Function): DB Exo act as molecular decoys that predominantly sequester soluble APRIL with partial BAFF attenuation, effectively disrupting the NF‐κB survival signaling axis and suppressing myeloma cell ...
Yuqing Zeng +5 more
wiley +1 more source
New approaches for the prevention of rejection and graft-vs.-host disease in clinical bone marrow transplantation. [PDF]
, 1986 The two major barriers to successful allogeneic bone marrow transplantation (BMT) in animals and man are graft-vs.-host disease (GVHD) and the risk of graft rejection.
Naparstek, E +9 more
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