Results 61 to 70 of about 7,424,852 (301)
CD4+FOXP3+ Regulatory T Cell Therapies in HLA Haploidentical Hematopoietic Transplantation
Frontiers in Immunology, 2019 Since their discovery CD4+FOXP3+ regulatory T cells (Tregs) represented a promising tool to induce tolerance in allogeneic hematopoietic cell transplantation.
Antonella Mancusi +3 more
doaj +1 more source
Human Mesenchymal Stem Cell Therapy for Acute Graft Versus Host Disease [PDF]
, 2016 Acute graft versus host disease (GVHD) is the most critical complication after allogeneic hematopoietic stem cell transplantation (allo-HSCT). The understanding of major histocompatibility complex (MHC) and the development of acute GVHD prophylaxis have ...
Miura, Yasuo, Yoshioka, Satoshi
core +1 more source
Making the Case for Organ‐on‐Chip Platforms in Long‐Acting Therapeutics Development
Advanced Healthcare Materials, EarlyView.LATs release drug from a tissue‐resident depot over weeks to months, improving adherence, but their development is hampered by preclinical models that cannot reproduce the coupled tissue processes, sustained release, local microenvironment change, interstitial transport, immune and foreign‐body responses, and clearance that govern depot performance in ...
Charlie Gowans +7 more
wiley +1 more source
Frontiers in Dentistry, 2017 Objectives: Graft-versus-host disease (GVHD) is among the most frequent complications of allogeneic hematopoietic stem cell transplantation (HSCT). GVHD has several clinical manifestations in the oral cavity, including painful desquamative erythema ...
Arash Mansourian +4 more
doaj
MiR-146a and miR-155 Expression Levels in Acute Graft-Versus-Host Disease Incidence
Frontiers in Immunology, 2016 Allogeneic haematopoietic stem cell transplantation (allo-HSCT) is a curative treatment for numerous haematological malignancies. However, acute graft-versus-host disease (aGVHD) is still the major complication causing mortality.
Sadaf eAtarod +8 more
doaj +1 more source
Advanced Materials for Biologics Delivery to Brain Tumors
Advanced Materials, EarlyView.Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng +4 more
wiley +1 more source
Frontiers in Immunology, 2013 A central objective in organ transplantation and the treatment or prevention of autoimmune disease is the achievement of antigen-specific immune tolerance.
Erin E Hillhouse +2 more
doaj +1 more source
Using Gene Editing Approaches to Fine-Tune the Immune System
Frontiers in Immunology, 2020 Genome editing technologies not only provide unprecedented opportunities to study basic cellular system functionality but also improve the outcomes of several clinical applications.
Kristina Pavlovic +12 more
doaj +1 more source
Transfusion-associated graft-vs-host disease – A case report [PDF]
, 2016 Transfusion-associated graft-vs-host disease (TAGVHD) is a rare complication of blood transfusion. Unlike GVHD associated with hematopoietic stem cell transplantation TA-GVHD involves the patient's bone marrow and leads to bone marrow aplasia.
Bhattacharyya, Jina; Department of Clinical Hematology, Gauhati Medical College, Guwahati, India +5 more
core +1 more source
Advanced Materials, EarlyView.This study presents the first demonstration of stable sub‐50‐micron single‐cell GPM vesicles fabricated through the intrinsic self‐assembly of an amphiphilic copolymer. Hierarchical assembly of cell containing GPM vesicles into microspheres enable tunable, sustained cell delivery with immune protection.
Viola B. Morris +11 more
wiley +1 more source