Results 61 to 70 of about 160,953 (345)

High-risk corneal allografts : A therapeutic challenge [PDF]

, 2016
Peer reviewedPublisher ...
Forrester, John V, Griffith, May, Kuffová, Lucia, Rajendran, Vijayalakshmi, Yu, Tian   +4 more
core   +1 more source

Efficacy of Triple Prophylaxis for Prevention of Graft-Versus-Host Disease in Matched Sibling Allogeneic Peripheral Blood Hematopoietic Stem Cell Transplantation in Pediatric Patients

International Journal of Medical Students, 2023
BACKGROUND: Graft-versus-host disease (GVHD) continues to compromise the overall success of allogenic hematopoietic stem cell transplantation. It is the most important cause of morbidity and non-relapse mortality after allogeneic hematopoietic stem cell
Fernando Tienda-López, Mariana Díaz-Ruiz, Jorge Marcos-García, Óscar González-Llano, Valentine Jiménez-Antolinez   +4 more
doaj   +1 more source

Ruxolitinib treatment for steroid refractory acute and chronic graft vs host disease in children: Clinical and immunological results

American journal of hematology/oncology, 2018
Ruxolitinib is a promising treatment for steroid refractory graft‐vs‐host disease (GvHD). However, data concerning effects on T cells are probably involved in increased risk of opportunistic infections.
M. González Vicent, B. Molina, J. González de Pablo, A. Castillo, M. Díaz   +4 more
semanticscholar   +1 more source

Polymorphism in TGFB1 is associated with worse non-relapse mortality and overall survival after stem cell transplantation with unrelated donors. [PDF]

, 2015
Transforming growth factor beta-1, encoded by the TGFB1 gene, is a cytokine that plays a central role in many physiological and pathogenic processes.
Apperley, JF, Arrieta-Bolaños, E, Kirkland, K, Mackinnon, S, Madrigal, JA, Marks, DI, Marsh, SG, Mayor, NP, McQuaker, G, Perry, J, Potter, MN, Russell, NH, Shaw, BE, Thomson, K   +13 more
core   +2 more sources

Acute Graft-vs.-Host Disease-Associated Endothelial Activation in vitro Is Prevented by Defibrotide

Frontiers in Immunology, 2019
Angiogenesis and endothelial activation and dysfunction have been associated with acute graft-vs.-host disease (aGVHD), pointing to the endothelium as a potential target for pharmacological intervention.
J. Martínez-Sánchez, H. Hamelmann, M. Palomo, Enrique Mir, A. Moreno-Castaño, Sergi Torramade, M. Rovira, G. Escolar, S. Cordes, Martina Kalupa, Sarah Mertlitz, Katarina Riesner, E. Carreras, Olaf Penack, M. Díaz-Ricart   +14 more
semanticscholar   +1 more source

The Evolution of T Cell Depleted Haploidentical Transplantation

Frontiers in Immunology, 2019
Work on bone marrow transplantation from haploidentical donor has been proceeding for over 20 years all over the world and new transplant procedures have been developed. To control both graft rejection and graft vs.
Franco Aversa, Antonio Pierini, Loredana Ruggeri, Massimo Fabrizio Martelli, Andrea Velardi   +4 more
doaj   +1 more source

Neutrophil extracellular traps (NETs) contribute to pathological changes of ocular graft-vs.-host disease (oGVHD) dry eye: Implications for novel biomarkers and therapeutic strategies.

The ocular surface, 2019
PURPOSE To investigate the role of neutrophil extracellular traps (NETs) and NET-associated proteins in the pathogenesis of oGVHD and whether dismantling of NETs with heparin reduces those changes.
Seungwon An, Ilangovan Raju, Bayasgalan Surenkhuu, Jieun Kwon, S. Gulati, M. Karaman, A. Pradeep, Satyabrata Sinha, Christine S. Mun, Sandeep Jain   +9 more
semanticscholar   +1 more source

Immune reconstitution and graft-versus-host reactions in rat models of allogeneic hematopoietic cell transplantation

Frontiers in Immunology, 2012
Allogeneic hematopoietic cell transplantation (alloHCT) extends the lives of thousands of patients who would otherwise succumb to hematopoietic malignancies such as leukemias and lymphomas, aplastic anemia and disorders of the immune system.
Severin eZinöcker, Severin eZinöcker, Ralf eDressel, Xiao-Nong eWang, Anne Mary Dickinson, Bent eRolstad   +5 more
doaj   +1 more source

Activated CD4 + T lymphocyte is a potential biomarker for acute graft-vs.-host disease after hematopoietic stem cell transplantation in children with transfusion-dependent β-thalassemia

Frontiers in Pediatrics, 2022
BackgroundAcute graft-vs.-host disease (aGVHD) is still one of the most common and life-threatening complications of allogeneic hematopoietic stem cell transplantation (HSCT).
Ken Huang, Jianming Luo
doaj   +1 more source

Stool Microbiota at Neutrophil Recovery Is Predictive for Severe Acute Graft vs Host Disease After Hematopoietic Cell Transplantation

Clinical Infectious Diseases, 2017
Low alpha diversity in stool microbiota at neutrophil recovery associates with increased severe graft-versus-host disease (GVHD), greater abundance of oral Actinobacteria or Firmicutes, and decreased abundance of intestinal Lachnospiraceae in stool ...
J. Golob, S. Pergam, S. Srinivasan, T. Fiedler, Congzhou Liu, Kristina Garcia, M. Mielcarek, Daisy L. Ko, Sarah Aker, Sara R Marquis, Tillie Loeffelholz, Anna M. Plantinga, Michael C. Wu, Kevin Celustka, A. Morrison, M. Woodfield, D. Fredricks   +16 more
semanticscholar   +1 more source