Complement and CD4+ T cells drive context-specific corneal sensory neuropathy
eLife, 2019 Whether complement dysregulation directly contributes to the pathogenesis of peripheral nervous system diseases, including sensory neuropathies, is unclear.
Derek J Royer +7 more
doaj +1 more source
Lethal graft-vs-host disease induced by a class II MHC antigen only disparity is not mediated by cytotoxic T cells. [PDF]
, 1988 Dwain L. Thiele +2 more
openalex +1 more source
High‐Throughput Strategies for Streamlining Lipid Nanoparticle Development Pipeline
Advanced Science, EarlyView.This review highlights emerging state‐of‐the‐art high‐throughput strategies for optimising lipid nanoparticle formulation. By integrating combinatorial design, characterization, in vitro/in vivo screening, automation, and machine learning into a closed‐loop framework, it provides a roadmap to streamline discovery and accelerate the translation of ...
Lois Lam +3 more
wiley +1 more source
Looking into nerve damage in the cornea
eLife, 2019 Interactions between T helper cells and the complement system promote loss of sensory neurons in the eye.
Mihaela Gadjeva
doaj +1 more source
Features of T cells causing H-2-restricted lethal graft-vs.-host disease across minor histocompatibility barriers. [PDF]
, 1982 Robert Korngold, Jonathan Sprent
openalex +1 more source
Tacrolimus in pediatric renal transplantation [PDF]
, 1996 Tacrolimus was used as the primary immunosuppressive agent in 69 pediatric renal transplantations between December 17, 1989, and June 30, 1995. Children undergoing concomitant or prior liver and/or intestinal transplantation were excluded from analysis ...
Ellis, D +12 more
core +1 more source
Photobiomodulation Strengthens Muscles via Its Dual Functions in Gut Microbiota
Advanced Science, EarlyView.Non‐invasive photobiomodulation therapy (PBMT) enhances muscle endurance by rewiring the gut‐muscle axis. PBMT preserves gut epithelial integrity and enriches beneficial anaerobes, driving metabolites such as butyrate, spermidine, and L‐carnitine that supercharge mitochondrial energy in skeletal muscles.
Prabhat Upadhyay +3 more
wiley +1 more source
IFN-beta production by macrophages obtained from mice undergoing graft vs host disease. [PDF]
, 1988 Mark Cleveland +2 more
openalex +1 more source
Advanced Science, EarlyView.The origin and functional heterogeneity of pericytes in glioblastoma (GBM) remain unclear. This study identifies tumor‐originated pericytes (T‐PCs) and normal‐originated pericytes as two distinctive populations in human GBM using single‐cell RNA‐sequencing.
Cuiying Chu +16 more
wiley +1 more source
Effect of selective T cell depletion of host and/or donor bone marrow on lymphopoietic repopulation, tolerance, and graft-vs-host disease in mixed allogeneic chimeras (B10 + B10.D2----B10). [PDF]
, 1986 S T Ildstad +5 more
openalex +1 more source