Results 21 to 30 of about 41,957 (165)

Inflammatory Cytokine Networks in Gastrointestinal Tract Graft vs. Host Disease

Frontiers in Immunology, 2019
Graft vs. host disease (GVHD) is the major non-relapse complication associated with allogeneic hematopoietic stem cell transplantation (HSCT). Damage to the gastrointestinal (GI) tract from acute GVHD is a particularly serious event that can result in ...
Clint Piper, William R. Drobyski, William R. Drobyski   +2 more
doaj   +1 more source

The Evolution of T Cell Depleted Haploidentical Transplantation

Frontiers in Immunology, 2019
Work on bone marrow transplantation from haploidentical donor has been proceeding for over 20 years all over the world and new transplant procedures have been developed. To control both graft rejection and graft vs.
Franco Aversa, Antonio Pierini, Loredana Ruggeri, Massimo Fabrizio Martelli, Andrea Velardi   +4 more
doaj   +1 more source

Immune reconstitution and graft-versus-host reactions in rat models of allogeneic hematopoietic cell transplantation

Frontiers in Immunology, 2012
Allogeneic hematopoietic cell transplantation (alloHCT) extends the lives of thousands of patients who would otherwise succumb to hematopoietic malignancies such as leukemias and lymphomas, aplastic anemia and disorders of the immune system.
Severin eZinöcker, Severin eZinöcker, Ralf eDressel, Xiao-Nong eWang, Anne Mary Dickinson, Bent eRolstad   +5 more
doaj   +1 more source

Activated CD4 + T lymphocyte is a potential biomarker for acute graft-vs.-host disease after hematopoietic stem cell transplantation in children with transfusion-dependent β-thalassemia

Frontiers in Pediatrics, 2022
BackgroundAcute graft-vs.-host disease (aGVHD) is still one of the most common and life-threatening complications of allogeneic hematopoietic stem cell transplantation (HSCT).
Ken Huang, Jianming Luo
doaj   +1 more source

Macrophage regulation of graft-vs-host disease

World Journal of Clinical Cases, 2020
Hematopoietic stem cell transplantation has become a curative choice of many hematopoietic malignancy, but graft-vs-host disease (GVHD) has limited the survival quality and overall survival of hematopoietic stem cell transplantation. Understanding of the immune cells' reaction in pathophysiology of GVHD has improved, but a review on the role of ...
Hong, Ya-Qun, Wan, Bo, Li, Xiao-Fan
openaire   +2 more sources

Severe Liver Dysfunction after Donor Lymphocyte Infusion for Relapsed Multiple Myeloma

The Korean Journal of Gastroenterology
Donor lymphocyte infusion (DLI) is performed to augment an anti-tumor immune response or ensure donor stem cells remain engrafted following allogeneic stem cell transplantation but may induce graft-versus-host disease (GVHD) involving skin, intestine ...
Tae-Hoon No, Nae-Yun Heo, Seung Ha Park, Joon Hyuk Choi, Junghwan Lee, Sung Nam Lim, Seon Yang Park   +6 more
doaj   +1 more source

Bortezomib-based immunosuppression after reduced-intensity conditioning hematopoietic stem cell transplantation: randomized phase II results

Haematologica, 2018
Aprior phase I/II trial of bortezomib/tacrolimus/methotrexate prophylaxis after human leukocyte antigen (HLA)-mismatched reduced intensity conditioning allogeneic hematopoietic stem cell transplantation documented low acute graft-versus-host disease ...
John Koreth, Haesook T. Kim, Paulina B. Lange, Samuel J. Poryanda, Carol G. Reynolds, Sharmila Chamling Rai, Philippe Armand, Corey S. Cutler, Vincent T. Ho, Brett Glotzbecker, Rushdia Yusuf, Sarah Nikiforow, Yi-Bin Chen, Bimalangshu Dey, Malgorzata McMasters, Jerome Ritz, Bruce R. Blazar, Robert J. Soiffer, Joseph H. Antin, Edwin P. Alyea   +19 more
doaj   +1 more source

Review of Cutaneous Graft-vs-Host Disease

Actas Dermo-Sifiliográficas (English Edition), 2016
Graft-vs-host disease (GVHD) is a multisystem disease that arises as a complication of allogeneic hematopoietic stem cell transplant. It is due to recognition of the recipient's tissues by immune cells from the donor. The skin and mucous membranes are the organs most commonly affected.
Ballester-Sánchez R, Navarro-Mira M, Sanz-Caballer J, Botella-Estrada R   +3 more
openaire   +3 more sources

Ruxolitinib in steroid refractory graft-vs.-host disease: a case report

Journal of Hematology & Oncology, 2016
Background Allogeneic hematopoietic stem cell transplantation (HSCT) is potentially curative in a variety of hematological malignancies. Graft-vs.-host disease (GvHD) remains a life-threatening complication.
Enrico Maffini, Luisa Giaccone, Moreno Festuccia, Lucia Brunello, Ilaria Buondonno, Dario Ferrero, Mario Boccadoro, Chiara Dellacasa, Alessandro Busca, Domenico Novero, Benedetto Bruno   +10 more
doaj   +1 more source

Dendritic Cell Regulation of Graft-Vs.-Host Disease: Immunostimulation and Tolerance

Frontiers in Immunology, 2019
Graft-vs.-host disease (GVHD) remains a significant cause of morbidity and mortality after allogeneic hematopoietic stem cell transplantation (allo-HSCT).
Hongshuang Yu, Yuanyuan Tian, Ying Wang, Shin Mineishi, Yi Zhang, Yi Zhang   +5 more
doaj   +1 more source